[HTML][HTML] Prenatal, obstetric and perinatal factors associated with the development of childhood-onset type 2 diabetes

J Halipchuk, B Temple, A Dart, D Martin… - Canadian journal of …, 2018 - Elsevier
Objective To explore associations among prenatal, obstetric and perinatal factors and the
development of childhood-onset type 2 diabetes. Methods This retrospective, case-control …

PPARα and PPARβ/δ are negatively correlated with proinflammatory markers in leukocytes of an obese pediatric population

K Vargas-Sánchez, L Vargas, Y Urrutia, I Beltrán… - Journal of …, 2020 - Springer
Background Obesity configures a pathophysiological profile that predisposes the
development of metabolic and cardiovascular diseases, critically impacting public health …

Type 2 diabetes in indigenous Australian children and adolescents

LJ Maple‐Brown, AK Sinha… - Journal of paediatrics and …, 2010 - Wiley Online Library
Rates of type 2 diabetes are higher among Indigenous than non‐Indigenous Australian
children and adolescents. Presentation may be incidental, part of obesity investigation …

Understanding the potential contribution of a third “T” to FITT exercise prescription: the case of timing in exercise for obesity and cardiometabolic management in …

RER Reid, D Thivel, ME Mathieu - … Physiology, Nutrition, and …, 2019 - cdnsciencepub.com
Currently, exercise prescription relies heavily on parameters included in the FITT principle:
frequency, intensity, time (duration), and type of exercise. In this paper, the benefits of …

Pharmacology and tolerability of a single dose of exenatide in adolescent patients with type 2 diabetes mellitus being treated with metformin: a randomized, placebo …

J Malloy, E Capparelli, M Gottschalk, X Guan… - Clinical …, 2009 - Elsevier
Objective: This study assessed the pharmacokinetics, pharmacodynamics, and tolerability of
single doses of exenatide in adolescent patients with type 2 diabetes mellitus (T2DM) …

Sodium Glucose Transporter-2 Inhibitors (SGLT2Is)-TLRs Axis Modulates Diabetes

A Niknejad, Y Hosseini, HS Shamsnia… - Cell Biochemistry and …, 2023 - Springer
Diabetes affects millions of people worldwide and is mainly associated with impaired insulin
function. To date, various oral anti-diabetic drugs have been developed, of which, the …

Treatment of pediatric type 2 diabetes

JD Smith, E Mills, SE Carlisle - Annals of Pharmacotherapy, 2016 - journals.sagepub.com
Objective: To review the current literature for the efficacy and safety of available treatments
for type 2 diabetes (T2DM) in the pediatric population. Data Sources: A search from January …

Real-life glycemic control in children with type 2 diabetes: a population-based study

J Meyerovitch, M Zlotnik, M Yackobovitch-Gavan… - The Journal of …, 2017 - Elsevier
Objectives To characterize children and adolescents with type 2 diabetes mellitus (T2DM)
insured by a large health maintenance organization, and to identify variables associated …

Preliminary analysis of immune activation in early onset type 2 diabetes

JD Rempel, J Packiasamy, HJ Dean… - … journal of circumpolar …, 2013 - Taylor & Francis
Introduction First Nations and other Aboriginal children are disproportionately affected by
cardiometabolic diseases, including type 2 diabetes (T2D). In T2D, the disruption of insulin …

Genetic contributions to childhood obesity: association of candidate gene polymorphisms and overweight/obesity in Korean preschool children

KH Yoo, HE Yim, ES Bae… - Journal of Korean …, 2017 - synapse.koreamed.org
This study was aimed to investigate the association of candidate gene polymorphisms and
obesity or overweight in young Korean children. A total of 190 Korean preschool children …