Severe chronic rhinosinusitis with nasal polyps (CRSwNP) is a debilitating disease with a
significant impact on the quality of life (QoL). It is typically characterized by a type 2 …

Type 2 inflammation is characterized by overexpression and heightened activity of type 2
cytokines, mediators and cells that drive neuroimmune activation and sensitization to …

Objective This narrative review analyses factors affecting recurrence of Chronic
rhinosinusitis with nasal polyps (CRSwNP) after surgery, such as type, extension and …

Introduction Olfactory dysfunction (OD) is a typical symptom of chronic rhinosinusitis (CRS),
which adversely affects the patient's quality of life and results in mood depression. Studies …

Background Nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease
(N-ERD) comprises the triad of chronic rhinosinusitis with nasal polyps, asthma and …

Heterogeneity in outcomes used in clinical trials prevents meta-analysis and contributes to
research waste. Core outcome sets aim to address this by defining a small number of …

The human sense of smell is the unique sense through which the olfactory system can
identify aromatic molecules within the air and provide a taste sensation. Still, also it plays an …

Abstract Purpose of Review Mechanical nasal obstruction (MNO) is a prevalent condition
with a high impact on patient's quality-of-life (QoL) and socio-economic burden. The aim of …

Sensory cells that specialize in transducing olfactory and gustatory stimuli are renewed
throughout life and can regenerate after injury unlike their counterparts in the mammalian …

The olfactory epithelium (OE) is directly exposed to environmental agents entering the nasal
cavity, leaving OSNs prone to injury and degeneration. The causes of olfactory dysfunction …