Introduction: Piperine has various pharmacological effects and can modulate the functional
activity of metabolic enzymes and drug transporters. Consequently, there is a great interest …

Self-emulsifying drug delivery systems (SEDDS) are one of the proven methods to increase
solubility and bioavailability of poorly soluble drugs. SEDDS are isotropic mixtures …

Aims Aim of the study was to enhance the solubility of Chlorthalidone by developing beta-
cyclodextrin cross-linked hydrophilic nanomatrices. Main methods Nine different …

The present study is aimed at enhancing the solubility of rosuvastatin (RST) by designing
betacyclodextrin/polyvinypyrrolidone-co-poly (2-acrylamide-2-methylpropane sulphonic …

The aim of this study was to develop a dutasteride (DUT) solid dispersion (SD) using
hydrophilic substances to enhance its dissolution (%) and oral bioavailability in rats. DUT …

A novel, supersaturable self-microemulsifying drug delivery system (S-SMEDDS) was
successfully formulated to enhance the dissolution and oral absorption of valsartan (VST), a …

Drying is an indispensable operation in the preparation of pharmaceutical powders and
always remained one of the energetic tasks in the pharmaceutical industry. Improving the …

The aim of current research was to develop a solid self-emulsifying delivery system (SEDS)
to enhance the delivery of linseed oil and quercetin. The pseudo ternary phase diagram was …

A large proportion of new chemical moieties are poorly water-soluble. As a result, the
biggest challenge for researchers is to enhance the solubility and oral bioavailability of …

Morin hydrate (MH) is a promising flavonoid with diverse biological activities; unfortunately, it
finds limited clinical application due to its low water solubility. Herein, we developed a liquid …