The growth hormone–insulin-like growth factor-I axis in the diagnosis and treatment of growth disorders

WF Blum, A Alherbish, A Alsagheir… - Endocrine …, 2018 - ec.bioscientifica.com
The growth hormone (GH)–insulin-like growth factor (IGF)-I axis is a key endocrine
mechanism regulating linear growth in children. While paediatricians have a good …

Growth failure:'idiopathic'only after a detailed diagnostic evaluation

R Rapaport, JM Wit, MO Savage - Endocrine Connections, 2021 - ec.bioscientifica.com
The terms 'idiopathic short stature'(ISS) and 'small for gestational age'(SGA) were first used
in the 1970s and 1980s. ISS described non-syndromic short children with undefined …

Reduction in pediatric growth hormone deficiency and increase in central precocious puberty diagnoses during COVID 19 pandemics

M Peinkhofer, B Bossini, A Penco, M Giangreco… - Italian Journal of …, 2022 - Springer
Background While several studies have been published so far on the effect of COVID-19
pandemic on health care for non-COVID-19 diseases, to date no study evaluated the impact …

[HTML][HTML] Deciphering short stature in children

N Polidori, V Castorani, A Mohn… - Annals of pediatric …, 2020 - ncbi.nlm.nih.gov
Short stature is a common reason for referral to pediatric endocrinologists. Multiple factors,
including genetic, prenatal, postnatal, and local environmental factors, can impair growth …

Short stature diagnosis and referral

M Maghnie, JI Labarta, E Koledova… - Frontiers in …, 2018 - frontiersin.org
The “360° GH in Europe” meeting, which examined various aspects of GH diseases, was
held in Lisbon, Portugal, in June 2016. The Merck KGaA (Germany) funded meeting …

Digital health for supporting precision medicine in pediatric endocrine disorders: opportunities for improved patient care

L Fernandez-Luque, A Al Herbish… - Frontiers in …, 2021 - frontiersin.org
Digitalization of healthcare delivery is rapidly fostering development of precision medicine.
Multiple digital technologies, known as telehealth or eHealth tools, are guiding …

[HTML][HTML] Balanced assessment of growth disorders using clinical, endocrinological, and genetic approaches

MO Savage, HL Storr - Annals of Pediatric Endocrinology & …, 2021 - synapse.koreamed.org
Determining the pathogenesis of pediatric growth disorders is often challenging. In many
cases, no pathogenesis is identified, and a designation of idiopathic short stature is used …

[HTML][HTML] Digital technologies to improve the precision of paediatric growth disorder diagnosis and management

L Dunkel, L Fernandez-Luque, S Loche… - Growth Hormone & IGF …, 2021 - Elsevier
Paediatric disorders of impaired linear growth are challenging to manage, in part because of
delays in the identification of pathological short stature and subsequent referral and …

What is normal, healthy growth? Global health, human biology, and parental perspectives

AL Thompson - American Journal of Human Biology, 2021 - Wiley Online Library
Objectives The widespread variation seen in human growth globally stands at odds with the
global health perspective that young child growth should not vary across populations if …

Short stature and language development in the United Kingdom: a longitudinal analysis of children from the Millennium Cohort Study

J Freer, J Orr, JK Morris, R Walton, L Dunkel, HL Storr… - BMC medicine, 2022 - Springer
Background In low-and middle-income countries, poverty and impaired growth prevent
children from meeting their cognitive developmental potential. There are few studies …