Prospective study of hyperhomocysteinemia as an adverse cardiovascular risk factor in end-stage renal disease

A Moustapha, A Naso, M Nahlawi, A Gupta… - Circulation, 1998 - Am Heart Assoc
Background—Retrospective and case-control studies show that hyperhomocysteinemia is
an independent risk factor for atherosclerosis in patients with end-stage renal disease. We …

Effect of folate and mecobalamin on hip fractures in patients with stroke: a randomized controlled trial

Y Sato, Y Honda, J Iwamoto, T Kanoko, K Satoh - Jama, 2005 - jamanetwork.com
Context Stroke increases the risk of subsequent hip fracture by 2 to 4 times.
Hyperhomocysteinemia is a risk factor for both ischemic stroke and osteoporotic fractures in …

Blood levels of homocysteine and increased risks of cardiovascular disease: causal or casual?

WG Christen, UA Ajani, RJ Glynn… - Archives of internal …, 2000 - jamanetwork.com
Background Accumulating data from epidemiological studies suggest that individuals with
elevated blood levels of homocysteine have increased risks of cardiovascular disease. We …

How to read a paper: Assessing the methodological quality of published papers

T Greenhalgh - Bmj, 1997 - bmj.com
How to read a paper: Assessing the methodological quality of published papers | The BMJ Skip
to main content Intended for healthcare professionals Access provided by Google Indexer …

Homocysteine and neurologic disease

R Diaz-Arrastia - Archives of neurology, 2000 - jamanetwork.com
Over the last 10 years, there has been an explosion of interest in homocysteine, a sulfur-
containing amino acid that occupies a central location in the metabolic pathways of thiol …

[HTML][HTML] Serum total homocysteine concentrations in adolescent and adult Americans: results from the third National Health and Nutrition Examination Survey

PF Jacques, IH Rosenberg, G Rogers, J Selhub… - The American journal of …, 1999 - Elsevier
Background The elevation of circulating total homocysteine concentrations in a fasting state
is associated with an increased risk of occlusive vascular disease. Objective The primary …

Serum folate and risk of fatal coronary heart disease

HI Morrison, D Schaubel, M Desmeules, DT Wigle - Jama, 1996 - jamanetwork.com
Objective.—To assess the relationship between serum folate level and the risk of fatal
coronary heart disease (CHD) among men and women. Design.—Retrospective cohort …

[HTML][HTML] Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans

MR Olthof, PC Hollman, PL Zock, MB Katan - The American journal of …, 2001 - Elsevier
Background: In population studies, high intakes of coffee are associated with raised
concentrations of plasma homocysteine, a predictor of risk of cardiovascular disease …

Enzyme conversion immunoassay for determining total homocysteine in plasma or serum

F Frantzen, AL Faaren, I Alfheim… - Clinical chemistry, 1998 - academic.oup.com
A rapid and precise immunoassay for quantification of total homocysteine in blood samples
is presented. The method avoids the use of radioisotopes and chromatographic separations …

Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations

HJ Naurath, E Joosten, R Riezler, S Stabler, RH Allen… - The Lancet, 1995 - thelancet.com
In a prospective, multicentre, double-blind controlled study, the effect of an intramuscular
vitamin supplement containing 1 mg vitamin B12, 1· 1 mg folate, and 5 mg vitamin B6 on …