In 482 patients sequentially referred for diagnosis and therapy of hyperlipidemia, our
specific aim was to determine the prevalence of homocysteinemia, to assess whether it was …

We investigated total, free and protein-bound plasma homocysteine, cysteine and
cysteinylglycine in 13 subjects aged 24–29 y after a breakfast at 0900 h containing 15–18 g …

Hyperhomocysteinemia is a common finding in dialysis-dependent end-stage renal disease
(ESRD) patients, but its etiology and refractoriness to standard homocysteine-lowering B …

We examined the relationship between intake of food group (and supplement) sources of
folate and plasma folate and homocysteine concentrations among 885 elderly subjects in …

Homocysteine is a sulfur amino acid whose metabolism stands at the intersection of two
pathways: remethylation, which requires folic acid and vitamin B12 coenzymes; and …

Hyperhomocysteinemia is a risk factor for atherosclerosis and thrombosis and is inversely
related to plasma folate and vitamin B12 levels. We assessed the effects of vitamin …

Background Plasma homocysteine levels are modulated by nutritional and genetic factors,
among which is the enzyme methylenetetrahydrofolate reductase (MTHFR). A common …

Hyperhomocysteinaemia, defined as an abnormally high plasma homocysteine
concentration after an oral methionine load, is common in young (≤ 50 years) patients with …

Vitamin B-12 deficiency is present in up to 15% of the elderly population as documented by
elevated methylmalonic acid with or without elevated total homocysteine concentrations in …

Background Venous and arterial thromboembolism occurs in only about one third of patients
homozygous for homocystinuria, which suggests that other, contributory factors are …