Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine

P Dhyani, C Quispe, E Sharma, A Bahukhandi… - Cancer cell …, 2022 - Springer
Cancer, one of the leading illnesses, accounts for about 10 million deaths worldwide. The
treatment of cancer includes surgery, chemotherapy, radiation therapy, and drug therapy …

Therapeutic applications of curcumin in diabetes: a review and perspective

C Quispe, J Herrera-Bravo, Z Javed… - BioMed Research …, 2022 - Wiley Online Library
Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug
therapy as well as lifestyle changes. There is now growing scientific evidence to support the …

Paclitaxel: application in modern oncology and nanomedicine‐based cancer therapy

J Sharifi-Rad, C Quispe, JK Patra… - Oxidative medicine …, 2021 - Wiley Online Library
Paclitaxel is a broad‐spectrum anticancer compound, which was derived mainly from a
medicinal plant, in particular, from the bark of the yew tree Taxus brevifolia Nutt. It is a …

Plasma modification techniques for natural polymer-based drug delivery systems

P Bhatt, V Kumar, V Subramaniyan, K Nagarajan… - Pharmaceutics, 2023 - mdpi.com
Natural polymers have attracted significant attention in drug delivery applications due to
their biocompatibility, biodegradability, and versatility. However, their surface properties …

Diosgenin: an updated pharmacological review and therapeutic perspectives

P Semwal, S Painuli, T Abu-Izneid… - Oxidative medicine …, 2022 - Wiley Online Library
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain
a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high …

Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery

S Waheed, Z Li, F Zhang, A Chiarini, U Armato… - Journal of …, 2022 - Springer
The rapid advancement of nanomedicine and nanoparticle (NP) materials presents novel
solutions potentially capable of revolutionizing health care by improving efficacy …

Recent advances and limitations of mTOR inhibitors in the treatment of cancer

ES Ali, K Mitra, S Akter, S Ramproshad, B Mondal… - Cancer cell …, 2022 - Springer
Abstract The PI3K-Akt-mechanistic (formerly mammalian) target of the rapamycin (mTOR)
signaling pathway is important in a variety of biological activities, including cellular …

The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents

M Butnariu, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2022 - Wiley Online Library
Crocus species are mainly distributed in North Africa, Southern and Central Europe, and
Western Asia, used in gardens and parks as ornamental plants, while Crocus sativus …

Applications of chitosan-alginate-based nanoparticles—An up-to-date review

AG Niculescu, AM Grumezescu - Nanomaterials, 2022 - mdpi.com
Chitosan and alginate are two of the most studied natural polymers that have attracted
interest for multiple uses in their nano form. The biomedical field is one of the domains …

Urtica dioica‐Derived Phytochemicals for Pharmacological and Therapeutic Applications

Y Taheri, C Quispe, J Herrera-Bravo… - Evidence‐based …, 2022 - Wiley Online Library
Urtica dioica belongs to the Urticaceae family and is found in many countries around the
world. This plant contains a broad range of phytochemicals, such as phenolic compounds …