Efficacy of continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) and resistant hypertension (RH): Systematic review and meta …

G Labarca, A Schmidt, J Dreyse, J Jorquera… - Sleep medicine …, 2021 - Elsevier
Summary Approximately 70–85% of patients with resistant hypertension (RH) report
obstructive sleep apnea (OSA). However, whether therapy with continuous positive airway …

International consensus statement on obstructive sleep apnea

JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

Relationship between CPAP termination and all-cause mortality: a French nationwide database analysis

JL Pépin, S Bailly, P Rinder, D Adler, AV Benjafield… - Chest, 2022 - Elsevier
Background Randomized controlled trials have failed to demonstrate an effect of CPAP
therapy on mortality. However, these studies have a number of important limitations …

Sleep apnea physiological burdens and cardiovascular morbidity and mortality

G Labarca, D Vena, WH Hu, N Esmaeili… - American Journal of …, 2023 - atsjournals.org
Rationale: Obstructive sleep apnea is characterized by frequent reductions in ventilation,
leading to oxygen desaturations and/or arousals. Objectives: In this study, association of …

Obstructive sleep apnea and stroke: the mechanisms, the randomized trials, and the road ahead

S Javaheri, Y Peker, HK Yaggi, CLA Bassetti - Sleep medicine reviews, 2022 - Elsevier
When considered separately from cardiovascular disease, stroke is the third leading cause
of death in the US and is the leading cause of long-term disability in adults. New approaches …

Telemedicine interventions for CPAP adherence in obstructive sleep apnea patients: Systematic review and meta-analysis

G Labarca, A Schmidt, J Dreyse, J Jorquera… - Sleep Medicine …, 2021 - Elsevier
Continuous positive airway pressure (CPAP) is the preferred therapy in patients with
obstructive sleep apnea (OSA). However, data suggests treatment adherence is low. In …

A validation study of four different cluster analyses of OSA and the incidence of cardiovascular mortality in a Hispanic population

G Labarca, J Dreyse, C Salas, F Letelier, J Jorquera - Chest, 2021 - Elsevier
Background Previous studies reported a strong association between sleepiness-related
symptoms and comorbidities with poor cardiovascular outcomes among patients with …

Adherence to CPAP treatment and the risk of recurrent cardiovascular events: a meta-analysis

M Sánchez-De-La-Torre, E Gracia-Lavedan, ID Benitez… - Jama, 2023 - jamanetwork.com
Importance The effect of continuous positive airway pressure (CPAP) on secondary
cardiovascular disease prevention is highly debated. Objective To assess the effect of CPAP …

Current and novel treatment options for obstructive sleep apnoea

W Randerath, J de Lange, J Hedner… - ERJ open …, 2022 - Eur Respiratory Soc
Obstructive sleep apnoea is a challenging medical problem due to its prevalence, its impact
on quality of life and performance in school and professionally, the implications for risk of …

Chronic intermittent hypoxia-induced mitochondrial dysfunction mediates endothelial injury via the TXNIP/NLRP3/IL-1β signaling pathway

YR Yan, L Zhang, YN Lin, XW Sun, YJ Ding, N Li… - Free Radical Biology …, 2021 - Elsevier
Oxidative stress and inflammation induced by chronic intermittent hypoxia (CIH) are trigger
factors of cardiovascular diseases in patients with obstructive sleep apnea (OSA). This study …