Chagas cardiomyopathy: an update of current clinical knowledge and management: a scientific statement from the American Heart Association

MCP Nunes, A Beaton, H Acquatella, C Bern… - Circulation, 2018 - Am Heart Assoc
Background: Chagas disease, resulting from the protozoan Trypanosoma cruzi, is an
important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally …

Trypanosoma cruzi genetic diversity: Something new for something known about Chagas disease manifestations, serodiagnosis and drug sensitivity

B Zingales - Acta tropica, 2018 - Elsevier
The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …

Chagas' disease

C Bern - New England Journal of Medicine, 2015 - Mass Medical Soc
Chagas’ Disease | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical …

American trypanosomiasis (Chagas disease)

LE Echeverria, CA Morillo - Infectious Disease Clinics, 2019 - id.theclinics.com
Chagas disease (CD), also known as American trypanosomiasis, is a multisystemic disorder
that can affect the cardiovascular, digestive, and central nervous systems. 1 CD is caused by …

[HTML][HTML] Advances in the treatment of Chagas disease: Promising new drugs, plants and targets

P García-Huertas, N Cardona-Castro - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Chagas disease, caused by Trypanosoma cruzi, is treated with only two drugs;
benznidazole and nifurtimox. These drugs have some disadvantages, including their …

Chagas disease drug discovery: toward a new era

E Chatelain - Journal of biomolecular screening, 2015 - journals.sagepub.com
American trypanosomiasis, or Chagas disease, is the result of infection by the Trypanosoma
cruzi parasite. Endemic in Latin America where it is the major cause of death from …

Discrete typing units of Trypanosoma cruzi: Geographical and biological distribution in the Americas

N Velásquez-Ortiz, G Herrera, C Hernández, M Muñoz… - Scientific data, 2022 - nature.com
Chagas disease caused by Trypanosoma cruzi is a public health issue in Latin America.
This highly diverse parasite is divided into at least seven discrete typing units (DTUs) TcI …

The evolution of trypanosomatid taxonomy

A Kaufer, J Ellis, D Stark, J Barratt - Parasites & vectors, 2017 - Springer
Trypanosomatids are protozoan parasites of the class Kinetoplastida predominately
restricted to invertebrate hosts (ie possess a monoxenous life-cycle). However, several …

Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment

TK Mackey, BA Liang, R Cuomo, R Hafen… - Clinical microbiology …, 2014 - Am Soc Microbiol
In global health, critical challenges have arisen from infectious diseases, including the
emergence and reemergence of old and new infectious diseases. Emergence and …

Neglected tropical diseases: diagnosis, clinical management, treatment and control

J Utzinger, SL Becker, S Knopp, J Blum… - Swiss medical weekly …, 2012 - edoc.unibas.ch
Branded in 2005,'neglected tropical diseases' have gained traction in terms of advocacy,
interest for research, enhanced funding and political will for their control and eventual …