[HTML][HTML] Drug delivery systems for RNA therapeutics

K Paunovska, D Loughrey, JE Dahlman - Nature Reviews Genetics, 2022 - nature.com
RNA-based gene therapy requires therapeutic RNA to function inside target cells without
eliciting unwanted immune responses. RNA can be ferried into cells using non-viral drug …

Smart nanoparticles for cancer therapy

L Sun, H Liu, Y Ye, Y Lei, R Islam, S Tan… - Signal transduction and …, 2023 - nature.com
Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …

Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems

TH Baryakova, BH Pogostin, R Langer… - Nature Reviews Drug …, 2023 - nature.com
Poor medication adherence is a pervasive issue with considerable health and
socioeconomic consequences. Although the underlying reasons are generally understood …

Recent advances in transdermal drug delivery systems: A review

WY Jeong, M Kwon, HE Choi, KS Kim - Biomaterials research, 2021 - spj.science.org
Various non-invasive administrations have recently emerged as an alternative to
conventional needle injections. A transdermal drug delivery system (TDDS) represents the …

Evolution of drug delivery systems: From 1950 to 2020 and beyond

H Park, A Otte, K Park - Journal of Controlled Release, 2022 - Elsevier
Modern drug delivery technology began in 1952 with the advent of the Spansule® sustained-
release capsule technology, which can deliver a drug for 12 h after oral administration …

Tumor abnormality-oriented nanomedicine design

Q Zhou, J Xiang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Advances in drug delivery systems, challenges and future directions

TC Ezike, US Okpala, UL Onoja, CP Nwike, EC Ezeako… - Heliyon, 2023 - cell.com
Advances in molecular pharmacology and an improved understanding of the mechanism of
most diseases have created the need to specifically target the cells involved in the initiation …

Perspectives on recent advancements in energy harvesting, sensing and bio-medical applications of piezoelectric gels

T Vijayakanth, S Shankar, G Finkelstein-Zuta… - Chemical Society …, 2023 - pubs.rsc.org
The development of next-generation bioelectronics, as well as the powering of consumer
and medical devices, require power sources that are soft, flexible, extensible, and even …

Photon-controlled pyroptosis activation (photopyro): an emerging trigger for antitumor immune response

M Li, J Kim, H Rha, S Son, MS Levine… - Journal of the …, 2023 - ACS Publications
Pyroptosis refers to the process of gasdermin-mediated lytic programmed cell death (PCD)
characterized by the release of pro-inflammatory cytokines. Our knowledge of pyroptosis has …

Stimuli-responsive polymer-based nanosystems for cancer theranostics

D Wei, Y Sun, H Zhu, Q Fu - ACS nano, 2023 - ACS Publications
Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …