The oxidative pentose phosphate pathway in the heart: Regulation, physiologicla significance, and clinical implications

HG Zimmer - Basic research in cardiology, 1992 - Springer
The capacity of the oxidative pentose phosphate pathway (PPP) in the heart is small, since
the activity of glucose-6-phosphate dehydrogenase (G-6-PD), the first and rate-limiting …

Normalization of depressed heart function in rats by ribose

HG Zimmer - Science, 1983 - science.org
Severe constriction of the abdominal aorta and simultaneous injection of isoproterenol in
rats induced depression in heart function and reductions in cardiac adenosine triphosphate …

Protein synthesis in the isolated perfused rat heart: effects of mechanical work load, diastolic ventricular pressure and coronary pressure on amino acid incorporation …

T Takala - Basic Research in Cardiology, 1981 - Springer
The mechanisms involved in hypertrophy of the left ventricle were studied in Langendorff-
perfused rat hearts by measuring the ventricular protein synthesis and its transmural …

The effect of triiodothyronine on the cardiac mRNA

J Zähringer, A Klaubert - Journal of Molecular and Cellular Cardiology, 1982 - Elsevier
Cardiac hypertrophy was induced in rats by daily injections of L-triiodothyronine (0.2 mg/kg
body wt, sc, 1 to 3 days). Regression of hypertrophy was studied after 3 days of injection for …

Nucleotide precursors modify the effects of isoproterenol. Studies on heart function and cardiac adenine nucleotide content in intact rats.

HG Zimmer, A Schneider - Circulation research, 1991 - Am Heart Assoc
In closed-chest rats, isoproterenol (ISO, 25 mg/kg), 5 hours after subcutaneous
administration, increased heart rate by 53%, left ventricular (LV) dP/dtmax by 80%, and …

Correlation between haemodynamic and metabolic changes in three models of experimental cardiac hypertrophy

HG Zimmer - European Heart Journal, 1984 - academic.oup.com
Three models of cardiac hypertrophy (aortic constriction, application of isoproterenol, daily
injections of triiodothyronine) were characterized in haemodynamic and in metabolic terms …

Pyrimidine nucleotide metabolism in cardiac hypertrophy

A Rossi, J Aussedat, J Olivares, A Ray… - European Heart …, 1984 - academic.oup.com
Cardiac hypertrophy was induced in rats either by isoprenaline treatment or by experimental
abdominal aortic stenosis. In both models, the UTP content increased in the hypertrophying …

Morphometric, histochemical and autoradiographic studies on myocardial cells in experimental cardiac hypertrophy and ischemia

H Guski, R Meyer, JE Fernandez-Britto - Experimental pathology, 1991 - Elsevier
Experimental studies were conducted into 170 adult male Wistar rats for the purpose of
analysis of cellular adaptation processes of the myocardium to acute ischemia. One group of …

Die Regulation der Proteinsynthese am normalen Herzen und unter pathologischen Bedingungen

J Zähringer - Herzinsuffizienz, 1984 - Springer
Die Regulation der Proteinsynthese am normalen Herzen und unter pathologischen
Bedingungen | SpringerLink Skip to main content Advertisement SpringerLink Account Menu …

Isoproterenol-induced responses in the regional polyamine metabolism of the rat heart

L Selmeci, S Bardócz, Z Egyed - Biochemical and Biophysical Research …, 1982 - Elsevier
Rats were treated with a single dose of isoproterenol (25 mg/kg sc) and the levels of
polyamines determined in various parts (right ventricle, basis, medial part and apex of the …