[HTML][HTML] The potential role of RNA N6-methyladenosine in Cancer progression

T Wang, S Kong, M Tao, S Ju - Molecular cancer, 2020 - Springer
Abstract N6-methyladenosine (m6A) is considered the most common, abundant, and
conserved internal transcript modification, especially in eukaryotic messenger RNA (mRNA) …

The roles of DNA, RNA and histone methylation in ageing and cancer

EM Michalak, ML Burr, AJ Bannister… - Nature reviews Molecular …, 2019 - nature.com
Chromatin is a macromolecular complex predominantly comprising DNA, histone proteins
and RNA. The methylation of chromatin components is highly conserved as it helps …

m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome

Y Tang, K Chen, B Song, J Ma, X Wu, Q Xu… - Nucleic acids …, 2021 - academic.oup.com
Abstract N 6-Methyladenosine (m6A) is the most prevalent RNA modification on mRNAs and
lncRNAs. It plays a pivotal role during various biological processes and disease …

RNAInter v4. 0: RNA interactome repository with redefined confidence scoring system and improved accessibility

J Kang, Q Tang, J He, L Li, N Yang, S Yu… - Nucleic acids …, 2022 - academic.oup.com
Establishing an RNA-associated interaction repository facilitates the system-level
understanding of RNA functions. However, as these interactions are distributed throughout …

Gene2vec: gene subsequence embedding for prediction of mammalian N6-methyladenosine sites from mRNA

Q Zou, P Xing, L Wei, B Liu - Rna, 2019 - rnajournal.cshlp.org
N 6-Methyladenosine (m6A) refers to methylation modification of the adenosine nucleotide
acid at the nitrogen-6 position. Many conventional computational methods for identifying N 6 …

DirectRMDB: a database of post-transcriptional RNA modifications unveiled from direct RNA sequencing technology

Y Zhang, J Jiang, J Ma, Z Wei, Y Wang… - Nucleic Acids …, 2023 - academic.oup.com
With advanced technologies to map RNA modifications, our understanding of them has
been revolutionized, and they are seen to be far more widespread and important than …

RM2Target: a comprehensive database for targets of writers, erasers and readers of RNA modifications

X Bao, Y Zhang, H Li, Y Teng, L Ma… - Nucleic Acids …, 2023 - academic.oup.com
RNA modification is a dynamic and reversible process regulated by a series of writers,
erasers and readers (WERs). Abnormal changes of WERs will disrupt the RNA modification …

[HTML][HTML] RNA m6A demethylase FTO-mediated epigenetic up-regulation of LINC00022 promotes tumorigenesis in esophageal squamous cell carcinoma

Y Cui, C Zhang, S Ma, Z Li, W Wang, Y Li, Y Ma… - Journal of Experimental …, 2021 - Springer
Background Long non-coding RNA (LncRNA) controls cell proliferation and plays a
significant role in the initiation and progression of esophageal squamous cell carcinoma …

[HTML][HTML] METTL14 is required for exercise-induced cardiac hypertrophy and protects against myocardial ischemia-reperfusion injury

L Wang, J Wang, P Yu, J Feng, G Xu, X Zhao… - Nature …, 2022 - nature.com
RNA m6A modification is the most widely distributed RNA methylation and is closely related
to various pathophysiological processes. Although the benefit of regular exercise on the …

The biogenesis and precise control of RNA m6A methylation

H Huang, H Weng, J Chen - Trends in Genetics, 2020 - cell.com
N 6-Methyladenosine (m 6 A) is the most prevalent internal RNA modification in mRNA, and
has been found to be highly conserved and hard-coded in mammals and other eukaryotic …