[HTML][HTML] Virulence Regulation and Innate Host Response in the Pathogenicity of Vibrio cholerae

T Ramamurthy, RK Nandy… - Frontiers in Cellular …, 2020 - frontiersin.org
The human pathogen Vibrio cholerae is the causative agent of severe diarrheal disease
known as cholera. Of the more than 200 “O” serogroups of this pathogen, O1 and O139 …

[HTML][HTML] Biogenic green synthesis of MgO nanoparticles using Saussurea costus biomasses for a comprehensive detection of their antimicrobial, cytotoxicity against …

M Amina, NM Al Musayeib, NA Alarfaj, MF El-Tohamy… - PLoS …, 2020 - journals.plos.org
Distinct morphological MgO nanoparticles (MgONPs) were synthesized using biomasses of
Saussurea costus roots. The biomass of two varieties of Saussurea costus (Qustal hindi and …

Coral gasdermin triggers pyroptosis

S Jiang, Z Zhou, Y Sun, T Zhang, L Sun - Science Immunology, 2020 - science.org
Gasdermins are executioners of the inflammatory cell death pathway pyroptosis that has so
far been studied exclusively in vertebrates. In this study, we identified gasdermin E (GSDME) …

Structure, regulation, and host interaction of outer membrane protein U (OmpU) of Vibrio species

HA Ganie, A Choudhary, S Baranwal - Microbial Pathogenesis, 2022 - Elsevier
OmpU is a multimeric, cation selective outer membrane protein of Vibrio and related species
that non-covalently interact with peptidoglycan layer. Interaction of OmpU with human host …

[HTML][HTML] Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis

P Deo, SH Chow, ID Hay, O Kleifeld, A Costin… - PLoS …, 2018 - journals.plos.org
Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading
innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial …

[HTML][HTML] GSDMEa-mediated pyroptosis is bi-directionally regulated by caspase and required for effective bacterial clearance in teleost

H Xu, S Jiang, C Yu, Z Yuan, L Sun - Cell Death & Disease, 2022 - nature.com
Gasdermin (GSDM) is a family of pore-forming proteins that, after cleavage by caspase
(CASP), induce a type of programmed necrotic cell death called pyroptosis. Gasdermin E …

[HTML][HTML] Peptide-coated polyurethane material reduces wound infection and inflammation

AC Strömdahl, L Ignatowicz, G Petruk, M Butrym… - Acta Biomaterialia, 2021 - Elsevier
There is an urgent need for treatments that not only reduce bacterial infection that occurs
during wounding but that also target the accompanying excessive inflammatory response …

Rotation of Vibrio fischeri flagella produces outer membrane vesicles that induce host development

MS Aschtgen, JB Lynch, E Koch… - Journal of …, 2016 - Am Soc Microbiol
Using the squid-vibrio association, we aimed to characterize the mechanism through which
Vibrio fischeri cells signal morphogenesis of the symbiotic light-emitting organ. The symbiont …

[HTML][HTML] Biogenic silver nanoparticles: Assessment of their cytotoxicity, genotoxicity and study of capping proteins

M Wypij, T Jędrzejewski, M Ostrowski, J Trzcińska… - Molecules, 2020 - mdpi.com
The development of nanotechnology in the last two decades has led to the use of silver
nanoparticles (AgNPs) in various biomedical applications, including antimicrobial, anti …

The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways

K Mao, P Breen, G Ruvkun - Proceedings of the National …, 2022 - National Acad Sciences
Surveillance of Caenorhabditis elegans mitochondrial status is coupled to defense
responses such as drug detoxification, immunity, antiviral RNA interference (RNAi), and …