Advances in the structure, mechanism and targeting of chemoresistance-linked ABC transporters
Cancer cells frequently display intrinsic or acquired resistance to chemically diverse
anticancer drugs, limiting therapeutic success. Among the main mechanisms of this …
anticancer drugs, limiting therapeutic success. Among the main mechanisms of this …
The role of microRNAs in multidrug resistance of glioblastoma
Simple Summary Glioblastoma (GBM) is one of the most malignant types of central nervous
system tumor which accounts for more than 60% of all brain tumors in adults. Owing to poor …
system tumor which accounts for more than 60% of all brain tumors in adults. Owing to poor …
Natural compounds in liposomal nanoformulations of potential clinical application in glioblastoma
L Piwowarczyk, DT Mlynarczyk, V Krajka-Kuźniak… - Cancers, 2022 - mdpi.com
Simple Summary Glioma is a type of cancer that is the most common primary brain tumor in
adults. The prognosis is often unfavorable despite early detection and treatment. Therefore …
adults. The prognosis is often unfavorable despite early detection and treatment. Therefore …
The history of small extracellular vesicles and their implication in cancer drug resistance
S Palazzolo, V Canzonieri, F Rizzolio - Frontiers in Oncology, 2022 - frontiersin.org
Small extracellular vesicles (EVs) in the last 20 years are demonstrated to possess
promising properties as potential new drug delivery systems, biomarkers, and therapeutic …
promising properties as potential new drug delivery systems, biomarkers, and therapeutic …
Mechanisms of long non-coding RNAs in biological characteristics and aerobic glycolysis of glioma
N Zhao, J Zhang, Q Zhao, C Chen, H Wang - International Journal of …, 2021 - mdpi.com
Glioma is the most common and aggressive tumor of the central nervous system. The
uncontrolled proliferation, cellular heterogeneity, and diffusive capacity of glioma cells …
uncontrolled proliferation, cellular heterogeneity, and diffusive capacity of glioma cells …
Overcoming Resistance to Temozolomide in Glioblastoma: A Scoping Review of Preclinical and Clinical Data
Glioblastoma (GB) is the most common and most aggressive primary brain tumor in adults,
with an overall survival almost 14.6 months. Optimal resection followed by combined …
with an overall survival almost 14.6 months. Optimal resection followed by combined …
Regulation of temozolomide resistance via lncRNAs: Clinical and biological properties of lncRNAs in gliomas
S Li, X Xie, F Peng, J Du… - … Journal of Oncology, 2022 - spandidos-publications.com
Gliomas are a primary types of intracranial malignancies and are characterized by a poor
prognosis due to aggressive recurrence profiles. Temozolomide (TMZ) is an auxiliary …
prognosis due to aggressive recurrence profiles. Temozolomide (TMZ) is an auxiliary …
EGFRvIII promotes the proneural–mesenchymal transition of glioblastoma multiforme and reduces its sensitivity to temozolomide by regulating the NF-κB/ALDH1A3 …
ZF Shi, GZ Li, Y Zhai, CQ Pan, D Wang, MC Yu, C Liu… - Genes, 2023 - mdpi.com
(1) Background: Glioblastoma multiforme (GBM) is the most common and malignant
intracranial tumor in adults. At present, temozolomide (TMZ) is recognized as the preferred …
intracranial tumor in adults. At present, temozolomide (TMZ) is recognized as the preferred …
Role of long noncoding RNAs in the regulation of alternative splicing in glioblastoma
B Yadav, P Yadav, S Yadav, AK Pandey - Drug Discovery Today, 2024 - Elsevier
Glioblastoma multiforme (GBM) is a highly severe primary brain tumor. Despite extensive
research, effective treatments remain elusive. Long noncoding RNAs (lncRNAs) play a …
research, effective treatments remain elusive. Long noncoding RNAs (lncRNAs) play a …
Crosstalk between SOX Genes and Long Non-Coding RNAs in Glioblastoma
M Stevanovic, N Kovacevic-Grujicic, I Petrovic… - International Journal of …, 2023 - mdpi.com
Glioblastoma (GBM) continues to be the most devastating primary brain malignancy. Despite
significant advancements in understanding basic GBM biology and enormous efforts in …
significant advancements in understanding basic GBM biology and enormous efforts in …