Advances in the structure, mechanism and targeting of chemoresistance-linked ABC transporters

A Sajid, H Rahman, SV Ambudkar - Nature Reviews Cancer, 2023 - nature.com
Cancer cells frequently display intrinsic or acquired resistance to chemically diverse
anticancer drugs, limiting therapeutic success. Among the main mechanisms of this …

The role of microRNAs in multidrug resistance of glioblastoma

P Mahinfar, B Mansoori, D Rostamzadeh, B Baradaran… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma (GBM) is one of the most malignant types of central nervous
system tumor which accounts for more than 60% of all brain tumors in adults. Owing to poor …

Natural compounds in liposomal nanoformulations of potential clinical application in glioblastoma

L Piwowarczyk, DT Mlynarczyk, V Krajka-Kuźniak… - Cancers, 2022 - mdpi.com
Simple Summary Glioma is a type of cancer that is the most common primary brain tumor in
adults. The prognosis is often unfavorable despite early detection and treatment. Therefore …

The history of small extracellular vesicles and their implication in cancer drug resistance

S Palazzolo, V Canzonieri, F Rizzolio - Frontiers in Oncology, 2022 - frontiersin.org
Small extracellular vesicles (EVs) in the last 20 years are demonstrated to possess
promising properties as potential new drug delivery systems, biomarkers, and therapeutic …

Mechanisms of long non-coding RNAs in biological characteristics and aerobic glycolysis of glioma

N Zhao, J Zhang, Q Zhao, C Chen, H Wang - International Journal of …, 2021 - mdpi.com
Glioma is the most common and aggressive tumor of the central nervous system. The
uncontrolled proliferation, cellular heterogeneity, and diffusive capacity of glioma cells …

Overcoming Resistance to Temozolomide in Glioblastoma: A Scoping Review of Preclinical and Clinical Data

D Smerdi, M Moutafi, I Kotsantis, LC Stavrinou, A Psyrri - Life, 2024 - mdpi.com
Glioblastoma (GB) is the most common and most aggressive primary brain tumor in adults,
with an overall survival almost 14.6 months. Optimal resection followed by combined …

Regulation of temozolomide resistance via lncRNAs: Clinical and biological properties of lncRNAs in gliomas

S Li, X Xie, F Peng, J Du… - … Journal of Oncology, 2022 - spandidos-publications.com
Gliomas are a primary types of intracranial malignancies and are characterized by a poor
prognosis due to aggressive recurrence profiles. Temozolomide (TMZ) is an auxiliary …

EGFRvIII promotes the proneural–mesenchymal transition of glioblastoma multiforme and reduces its sensitivity to temozolomide by regulating the NF-κB/ALDH1A3 …

ZF Shi, GZ Li, Y Zhai, CQ Pan, D Wang, MC Yu, C Liu… - Genes, 2023 - mdpi.com
(1) Background: Glioblastoma multiforme (GBM) is the most common and malignant
intracranial tumor in adults. At present, temozolomide (TMZ) is recognized as the preferred …

Role of long noncoding RNAs in the regulation of alternative splicing in glioblastoma

B Yadav, P Yadav, S Yadav, AK Pandey - Drug Discovery Today, 2024 - Elsevier
Glioblastoma multiforme (GBM) is a highly severe primary brain tumor. Despite extensive
research, effective treatments remain elusive. Long noncoding RNAs (lncRNAs) play a …

Crosstalk between SOX Genes and Long Non-Coding RNAs in Glioblastoma

M Stevanovic, N Kovacevic-Grujicic, I Petrovic… - International Journal of …, 2023 - mdpi.com
Glioblastoma (GBM) continues to be the most devastating primary brain malignancy. Despite
significant advancements in understanding basic GBM biology and enormous efforts in …