Therapeutic approach of natural products that treat osteoporosis by targeting epigenetic modulation

G Zhang, Z Liu, Z Li, B Zhang, P Yao, Y Qiao - Frontiers in Genetics, 2023 - frontiersin.org
Osteoporosis (OP) is a metabolic disease that affects bone, resulting in a progressive
decrease in bone mass, quality, and micro-architectural degeneration. Natural products …

Phytochemicals and Their Usefulness in the Maintenance of Health

EV Rodríguez-Negrete, Á Morales-González… - Plants, 2024 - mdpi.com
Inflammation is the immune system's first biological response to infection, injury, or irritation.
Evidence suggests that the anti-inflammatory effect is mediated by the regulation of various …

Nuciferine-loaded chitosan hydrogel-integrated 3D-printed polylactic acid scaffolds for bone tissue engineering: A combinatorial approach

R Bharathi, G Harini, A Sankaranarayanan… - International Journal of …, 2023 - Elsevier
Critical-sized bone defects resulting from severe trauma and open fractures cannot
spontaneously heal and require surgical intervention. Limitations of traditional bone grafting …

The Therapeutic Potential of Two Egyptian Plant Extracts for Mitigating Dexamethasone-Induced Osteoporosis in Rats: Nrf2/HO-1 and RANK/RANKL/OPG Signals

SR Saleh, OM Saleh, AA El-Bessoumy, E Sheta… - Antioxidants, 2024 - mdpi.com
The prolonged use of exogenous glucocorticoids, such as dexamethasone (Dex), is the
most prevalent secondary cause of osteoporosis, known as glucocorticoid-induced …

[HTML][HTML] Pharmacological and mechanistic aspects of quercetin in osteoporosis

TT Deng, WY Ding, XX Lu, QH Zhang, JX Du… - Frontiers in …, 2024 - frontiersin.org
Osteoporosis (OP) is a bone disease associated with increasing age. Currently, the most
common medications used to treat OP are anabolic agents, anti-resorptive agents, and …

Exploring the potential role of genus Sophora in the management of osteoporosis: a phytochemical and biological review

SH Aly, AMM Elbadry, M El-Shazly… - Frontiers in Natural …, 2023 - frontiersin.org
Bone metabolism is characterized by an interplay between the deposition of bone matrix
and mineralization and the resorption process. Osteoporosis is a form of systemic metabolic …

Transcriptome and Metabolome Analysis of Isoquinoline Alkaloid Biosynthesis of Coptis chinensis in Different Years

X Min, T Zhu, X Hu, C Hou, J He, X Liu - Genes, 2023 - mdpi.com
Coptis chinensis is a perennial herb of the Ranunculaceae family. The isoquinoline alkaloid
is the main active component of C. chinensis, mainly exists in its rhizomes and has high …

A Mechanistic Study of the Osteogenic Effect of Arecoline in an Osteoporosis Model: Inhibition of Iron Overload-Induced Osteogenesis by Promoting Heme Oxygenase …

Z Jiang, L Deng, G Xiang, X Xu, Y Wang - Antioxidants, 2024 - mdpi.com
Iron overload-associated osteoporosis presents a significant challenge to bone health. This
study examines the effects of arecoline (ACL), an alkaloid found in areca nut, on bone …

长链非编码RNA 通过p38MAPK 信号通路直接或间接影响骨质疏松症

覃浩, 亢腾, 刘钢 - 中国组织工程研究, 2025 - cjter.com
长链非编码RNA 通过p38MAPK 信号通路直接或间接影响骨质疏松症 Page 1 Chinese Journal of
Tissue Engineering Research|Vol 29|No.1|January 2025|175 中国组织工程研究 Chinese Journal …

Natural products for the treatment of depression: Insights into signal pathways influencing the hypothalamic–pituitary–adrenal axis

J Liu, T Meng, C Wang, W Cheng, Q Zhang, G Cheng - Medicine, 2023 - journals.lww.com
Depression, a prevalent psychiatric malady, afflicts a substantial global demographic,
engendering considerable disease burden due to its elevated morbidity and mortality rates …