Emergence of resistance to traditional antibiotic treatments necessitates alternative delivery
systems. Teicoplanin is a glycopeptide antibiotic used in the treatments of serious infections …

Targeting and treating intracellular pathogen infections has been long-standing challenge,
particularly in light of the escalating prevalence of antimicrobial resistance. Herein, an …

When antibiotic-resistant pathogenic bacteria pose a high threat to human health, bacterial
multidrug efflux pumps become major contributors to the high-level antibiotic resistance in …

Bacterial infection is a huge threat to the health of human beings and animals. The abuse of
antibiotics has led to the occurrence of bacterial multidrug resistance, which has become a …

Macrophages are one of the main host cells of intracellular pathogens and the elimination of
intracellular bacteria (ICBs) relies on sufficient antibiotic concentrations inside infected …

Staphylococcus aureus is a primary pathogen responsible for causing postoperative
infections as it survives and persists in host cells, including osteoblasts and macrophages …

The worldwide increased bacterial resistance toward antimicrobial therapeutics has led
investigators to search for new therapeutic options. Some of the options currently exploited …

In the presented study, transportan 10 (TP10), an amphipathic cell penetrating peptide
(CPP) with high translocation activity, was conjugated with vancomycin (Van), which is …

A rationally designed mannosylated amphiphilic pillar [5] arene (Man@ AP5) self-assembles
into supramolecular vesicles with encapsulated vancomycin (Man@ AP5-Van), which target …

In a recent report, the World Health Organisation (WHO) classified antibiotic resistance as
one of the greatest threats to global health, food security, and development. Methicillin …