[HTML][HTML] Effects of polymers on the drug solubility and dissolution enhancement of poorly water-soluble rivaroxaban

MJ Choi, MR Woo, HG Choi, SG Jin - International Journal of Molecular …, 2022 - mdpi.com
The purpose of this study was to investigate the efficacy of hydrophilic polymers in a solid
dispersion formulation in improving the solubility and dissolution rate of rivaroxaban (RXB) …

Self-Generating nano-emulsification techniques for alternatively-routed, bioavailability enhanced delivery, especially for anti-cancers, anti-diabetics, and …

N Akhtar, SAA Mohammed, RA Khan, M Yusuf… - Journal of Drug Delivery …, 2020 - Elsevier
The self-generating nano-emulsifying drug delivery system (SNEDDS) is among the most
effective approaches to enhance the oral bioavailability of a therapeutic agent, especially of …

Comparison of three different aqueous microenvironments for enhancing oral bioavailability of sildenafil: solid self-nanoemulsifying drug delivery system, amorphous …

JS Kim, F Din, SM Lee, DS Kim, MR Woo… - International journal …, 2021 - Taylor & Francis
Background The purpose of this study was to screen various drug delivery systems for
improving the aqueous solubility and oral bioavailability of sildenafil. Three representative …

Cellulose: A promising and versatile Pickering emulsifier for healthy foods

L Liu, BO Ode Boni, MW Ullah, F Qi, X Li… - Food Reviews …, 2023 - Taylor & Francis
With a growing human population suffering from chronic diseases induced by inappropriate
diet and lifestyle, the market for healthy foods is flourishing over the past few years. Hence …

Comparative study between high-pressure homogenisation and Shirasu porous glass membrane technique in sildenafil base-loaded solid SNEDDS: effects on …

JS Kim, F ud Din, SM Lee, DS Kim, YJ Choi… - International Journal of …, 2021 - Elsevier
The purpose of this study was to compare two types of emulsification techniques in a solid
self-nanoemulsifying drug delivery system (SNEDDS); high-pressure homogenisation (HPH) …

Effects of different physicochemical characteristics and supersaturation principle of solidified SNEDDS and surface-modified microspheres on the bioavailability of …

JE Choi, JS Kim, MJ Choi, K Baek, MR Woo… - International Journal of …, 2021 - Elsevier
In this study, a solidified self-nanoemulsifying drug delivery system (solidified SNEDDS) and
surface-modified microspheres were developed for enhancing the oral bioavailability of …

Impact of carrier hydrophilicity on solid self nano-emulsifying drug delivery system and self nano-emulsifying granule system

JS Kim, F ud Din, HJ Cho, YJ Choi, MR Woo… - International Journal of …, 2023 - Elsevier
The purpose of this study was to investigate the impact of carrier hydrophilicity on solid self
nano-emulsifying drug delivery system (SNEDDS) and self nano-emulsifying granule system …

Comparison of the physicochemical properties, aqueous solubility, and oral bioavailability of rivaroxaban-loaded high-pressure homogenised and Shirasu porous …

MJ Choi, JS Kim, H Yu, MR Woo, JE Choi… - Journal of Molecular …, 2022 - Elsevier
This study aimed to compare high-pressure homogenization (HPH) and Shirasu porous
glass (SPG) membrane emulsification for enhancing the oral bioavailability of rivaroxaban …

Hydroxypropyl-β-cyclodextrin-based solid dispersed granules: A prospective alternative to conventional solid dispersion

JS Kim, F ud Din, YJ Choi, MR Woo, S Cheon… - International Journal of …, 2022 - Elsevier
The purpose of the present study was to develop hydroxypropyl-β-cyclodextrin (HP-β-CD)-
based solid dispersed granules as a superior system to solid dispersion. The solid …

[HTML][HTML] High-shear wet granulation of SMEDDS based on mesoporous carriers for improved carvedilol solubility

M Kovačević, I German Ilić, K Bolko Seljak… - Pharmaceutics, 2022 - mdpi.com
Mesoporous carriers are a convenient choice for the solidification of self-microemulsifying
drug delivery systems (SMEDDS) designed to improve the solubility of poorly water-soluble …