MDMA, serotonergic neurotoxicity, and the diverse functional deficits of recreational 'Ecstasy'users

AC Parrott - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Serotonergic neurotoxicity following MDMA is well-established in laboratory animals, and
neuroimaging studies have found lower serotonin transporter (SERT) binding in abstinent …

Hard boiled: alcohol use as a risk factor for MDMA-induced hyperthermia: a systematic review

J van Amsterdam, TM Brunt, M Pierce… - Neurotoxicity …, 2021 - Springer
Although MDMA (ecstasy) is a relatively safe recreational drug and is currently considered
for therapeutic use for the treatment of posttraumatic stress disorder (PTSD) and alcohol use …

Concurrent and simultaneous polydrug use: latent class analysis of an Australian nationally representative sample of young adults

LH Quek, GCK Chan, A White, JP Connor… - Frontiers in public …, 2013 - frontiersin.org
Background: Alcohol use and illicit drug use peak during young adulthood (around 18–29
years of age), but comparatively little is known about polydrug use in nationally …

Overview of the major classes of new psychoactive substances, psychoactive effects, analytical determination and conformational analysis of selected illegal drugs

V Lukić, R Micić, B Arsić, B Nedović… - Open Chemistry, 2021 - degruyter.com
The misuse of psychoactive substances is attracting a great deal of attention from the
general public. An increase use of psychoactive substances is observed among young …

Combination effects of amphetamines under hyperthermia‐the role played by oxidative stress

DD Da Silva, E Silva, H Carmo - Journal of Applied Toxicology, 2014 - Wiley Online Library
Rise in body temperature is a life‐threatening consequence of 3, 4‐
methylenedioxymethamphetamine (MDMA, ecstasy) abuse. We evaluated the impact of …

Fatal and non-fatal health incidents related to recreational ecstasy use

J van Amsterdam, E Pennings… - Journal of …, 2020 - journals.sagepub.com
Background: The recreational drug ecstasy (3, 4-methylenedioxymethamphetamine) is
currently used world-wide. Severe (including fatal) health incidents related to ecstasy have …

MDMA interactions with pharmaceuticals and drugs of abuse

E Papaseit, C Pérez-Mañá, M Torrens… - Expert Opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction: MDMA (3, 4-methylenedioxymethamphetamine), a synthetic ring-
substituted amphetamine, has become one of the most widely used recreational …

Pharmacokinetics and pharmacodynamics of 3, 4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug–drug …

SJ Rietjens, L Hondebrink, RHS Westerink… - Critical reviews in …, 2012 - Taylor & Francis
Clinical outcome following 3, 4-methylenedioxymethamphetamine (MDMA) intake ranges
from mild entactogenic effects to a life-threatening intoxication. Despite ongoing research …

MDMA alone affects sensorimotor and prepulse inhibition responses in mice and rats: tips in the debate on potential MDMA unsafety in human activity

M Marti, M Neri, S Bilel, M Di Paolo, R La Russa… - Forensic …, 2019 - Springer
Purpose MDMA is a psychoactive drug that has been increasingly abused worldwide, due to
its entactogenic properties. However, concerns on its safety exist, particularly regarding its …

Feasibility study of ethylone determination in seized samples using boron-doped diamond electrode associated with solid phase extraction

GL Scheel, FM de Oliveira, LLG de Oliveira… - Sensors and Actuators B …, 2018 - Elsevier
Ethylone is a synthetic cathinone recently found in illicit drugs, due to its similar central
nervous system-stimulation properties with 'ecstasy'. Due to the necessity of a rapid and …