Mitochondrial respiration is an energy producing process that involves the coordinated
action of several protein complexes embedded in the inner membrane to finally produce …

Lifestyle-related disorders, such as the metabolic syndrome, have become a primary risk
factor for the development of liver pathologies that can progress from hepatic steatosis …

We recently demonstrated, using yeast DNA microarrays, that mRNAs of polysomes that
coisolate with mitochondria code for a subset of mitochondrial proteins. The majority of these …

The inner mitochondrial membrane harbors a large number of proteins that display a wide
range of topological arrangements. The majority of these proteins are encoded in the cell's …

Mitochondria are organelles derived from α-proteobacteria over the course of one to two
billion years. Mitochondria from the major eukaryotic lineages display some variation in …

Proteins of the Oxa1/YidC/Alb3 family mediate the insertion of proteins into membranes of
mitochondria, bacteria, and chloroplasts. Here we report the identification of a second gene …

▪ Abstract The inner membranes of eubacteria and mitochondria, as well as the chloroplast
thylakoid membrane, contain essential proteins that function in oxidative phosphorylation …

Eukaryotic cytochrome c oxidase (CcO), the terminal component of the mitochondrial
electron transport chain is a heterooligomeric complex that belongs to the superfamily of …

Abstract The evolutionarily conserved YidC/Oxa1/Alb3 proteins are involved in the insertion
of membrane proteins in all domains of life. In plant mitochondria, individual knockouts of …

During the biogenesis of the mitochondrial inner membrane, most nuclear-encoded inner
membrane proteins are laterally released into the membrane by the TIM23 and the TIM22 …