Persistent depressive disorder is a chronic mood disorder that is common and often more
disabling than episodic major depression. In DSM-5, the term subsumes several chronic …

Objectives: To provide guidance for the management of mood disorders, based on scientific
evidence supplemented by expert clinical consensus and formulate recommendations to …

Purpose To review and synthesise prognostic indices that predict subsequent risk,
prescriptive indices that moderate treatment response, and mechanisms that underlie each …

Background: Depression is the most debilitating neuropsychiatric disorder with significant
impact on socio-occupational and well being of individual. The exact pathophysiology of …

To improve the 'personalized-medicine'approach to the treatment of depression, we need to
identify biomarkers that, assessed before starting treatment, predict future response to …

A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

Major depression (MD) is a common psychiatric disorder with a complex and multifactor
aetiology. Potential mechanisms associated with the pathogenesis of this disorder include …

A revision of the 2000 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken to …

Abstract Major Depressive Disorder (MDD, ICD-10: F-33) is a prevalent illness in which the
pathogenic mechanism remains elusive. Recently an important role has been attributed to …

Weight gain during antidepressant treatment can be either a sign of improvement in patients
who have weight loss as a symptom of depression or a residual symptom in patients who …