Mammalian cell transfection: the present and the future
TK Kim, JH Eberwine - Analytical and bioanalytical chemistry, 2010 - Springer
Transfection is a powerful analytical tool enabling study of the function of genes and gene
products in cells. The transfection methods are broadly classified into three groups; …
products in cells. The transfection methods are broadly classified into three groups; …
Functional nucleic acid sensors
Sensors are devices that respond to physical or chemical stimuli and produce detectable
signals. 1r4 They are a critical extension of human perception of the world in many aspects …
signals. 1r4 They are a critical extension of human perception of the world in many aspects …
RNA interference: biology, mechanism, and applications
N Agrawal, PVN Dasaradhi, A Mohmmed… - Microbiology and …, 2003 - Am Soc Microbiol
Double-stranded RNA-mediated interference (RNAi) is a simple and rapid method of
silencing gene expression in a range of organisms. The silencing of a gene is a …
silencing gene expression in a range of organisms. The silencing of a gene is a …
Catalytic nucleic acids: biochemistry, chemical biology, biosensors, and nanotechnology
Since the initial discovery of ribozymes in the early 1980s, catalytic nucleic acids have been
used in different areas. Compared with protein enzymes, catalytic nucleic acids are …
used in different areas. Compared with protein enzymes, catalytic nucleic acids are …
Engineered nucleic acids encoding a modified erythropoietin and their expression
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
46147671&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
46147671&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Antisense technologies: improvement through novel chemical modifications
J Kurreck - European journal of biochemistry, 2003 - Wiley Online Library
Antisense agents are valuable tools to inhibit the expression of a target gene in a sequence‐
specific manner, and may be used for functional genomics, target validation and therapeutic …
specific manner, and may be used for functional genomics, target validation and therapeutic …
Killing the messenger: short RNAs that silence gene expression
DM Dykxhoorn, CD Novina, PA Sharp - Nature reviews Molecular cell …, 2003 - nature.com
Short interfering RNAs can be used to silence gene expression in a sequence-specific
manner in a process that is known as RNA interference. The application of RNA interference …
manner in a process that is known as RNA interference. The application of RNA interference …
[图书][B] Introduction to nanoscience and nanotechnology
The maturation of nanotechnology has revealed it to be a unique and distinct discipline
rather than a specialization within a larger field. Its textbook cannot afford to be a chemistry …
rather than a specialization within a larger field. Its textbook cannot afford to be a chemistry …
Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy
Aptamers are single-stranded nucleic acid molecules that possess properties comparable to
those of protein monoclonal antibodies, and thus are clear alternatives to long established …
those of protein monoclonal antibodies, and thus are clear alternatives to long established …
siRNAs: applications in functional genomics and potential as therapeutics
Y Dorsett, T Tuschl - Nature reviews Drug discovery, 2004 - nature.com
Molecules that can specifically silence gene expression are powerful research tools. Much
effort has been put into the development of such molecules and has resulted in the creation …
effort has been put into the development of such molecules and has resulted in the creation …