How cells adopt different identities has long fascinated biologists. Signal transduction in
response to environmental cues results in the activation of transcription factors that …

Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally
regulate each other, are among the well-known cancer hallmarks. Recent evidence …

Modified parental histones are segregated symmetrically to daughter DNA strands during
replication and can be inherited through mitosis. How this may sustain the epigenome and …

Chromatin landscapes are disrupted during DNA replication and must be restored faithfully
to maintain genome regulation and cell identity. The histone H3-H4 modification landscape …

Propagation of the chromatin landscape across cell divisions is central to epigenetic cell
memory. Mechanistic analysis of the interplay between DNA replication, the cell cycle, and …

Melanogenesis is a complex process in which melanin is synthesized in melanocytes and
transported to keratinocytes, which involves multiple genes and signaling pathways …

One of the hallmarks of the cerebral cortex is the extreme diversity of interneurons,–. The two
largest subtypes of cortical interneurons, parvalbumin-and somatostatin-positive cells, are …

The most fundamental process for the perpetuation of a species is the transfer of information
from parent to offspring. Although genomic DNA contributes to the majority of the …

Zygnematophyceae are the algal sisters of land plants. Here we sequenced four genomes of
filamentous Zygnematophyceae, including chromosome-scale assemblies for three strains …

Sleep is essential to all animals with a nervous system. Nevertheless, the core cellular
function of sleep is unknown, and there is no conserved molecular marker to define sleep …