Novel thiophene Chalcones-Coumarin as acetylcholinesterase inhibitors: Design, synthesis, biological evaluation, molecular docking, ADMET prediction and …
A series of around eight novel chalcone based coumarin derivatives (23a-h) was designed,
subjected to in-silico ADMET prediction, synthesized, characterized by IR, NMR, Mass …
subjected to in-silico ADMET prediction, synthesized, characterized by IR, NMR, Mass …
Application of montmorillonite in bentonite as a pharmaceutical excipient in drug delivery systems
JH Park, HJ Shin, MH Kim, JS Kim, N Kang… - Journal of …, 2016 - Springer
Montmorillonite is a multifunctional clay mineral and a major component of bentonite.
Montmorillonite has been used in various industrial and pharmaceutical fields due to its …
Montmorillonite has been used in various industrial and pharmaceutical fields due to its …
Current trends on solid dispersions: past, present, and future
R Malkawi, WI Malkawi, Y Al-Mahmoud… - Advances in …, 2022 - Wiley Online Library
Solid dispersions have achieved significant interest as an effective means of enhancing the
dissolution rate and thus the bioavailability of a range of weakly water‐soluble drugs. Solid …
dissolution rate and thus the bioavailability of a range of weakly water‐soluble drugs. Solid …
[HTML][HTML] Emerging nanoformulation strategies for phytocompounds and applications from drug delivery to phototherapy to imaging
Over thousands of years, natural bioactive compounds derived from plants (bioactive
phytocompounds, BPCs) have been used worldwide to address human health issues …
phytocompounds, BPCs) have been used worldwide to address human health issues …
Novel solubility prediction models: Molecular fingerprints and physicochemical features vs graph convolutional neural networks
Predicting both accurate and reliable solubility values has long been a crucial but
challenging task. In this work, surrogated model-based methods were developed to …
challenging task. In this work, surrogated model-based methods were developed to …
The Photosensitizer Temoporfin (mTHPC) – Chemical, Pre‐clinical and Clinical Developments in the Last Decade†‡
A Wiehe, MO Senge - Photochemistry and Photobiology, 2023 - Wiley Online Library
This review follows the research, development and clinical applications of the
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …
Nanostructured lipid carriers: versatile oral delivery vehicle
Oral delivery is the most accepted and economical route for drug administration and leads to
substantial reduction in dosing frequency. However, this route still remains a challenge for …
substantial reduction in dosing frequency. However, this route still remains a challenge for …
In silico evaluation of food‐derived carotenoids against SARS‐CoV‐2 drug targets: Crocin is a promising dietary supplement candidate for COVID‐19
The current COVID‐19 pandemic is severely threatening public healthcare systems around
the globe. Some supporting therapies such as remdesivir, favipiravir, and ivermectin are still …
the globe. Some supporting therapies such as remdesivir, favipiravir, and ivermectin are still …
Nanonization techniques to overcome poor water-solubility with drugs
FLO Da Silva, MBDF Marques, KC Kato… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction Most drugs used in therapy have low water-solubility, a factor that could reduce
their dissolution rate and oral bioavailability, representing a challenge in pharmaceutical …
their dissolution rate and oral bioavailability, representing a challenge in pharmaceutical …
Supercritical antisolvent process for pharmaceutical applications: A review
P Franco, I De Marco - Processes, 2020 - mdpi.com
The supercritical antisolvent (SAS) technique has been widely employed in the biomedical
field, including drug delivery, to obtain drug particles or polymer-based systems of …
field, including drug delivery, to obtain drug particles or polymer-based systems of …