Challenges and strategies in drug delivery systems for treatment of pulmonary infections
Inhalation therapy has been reported as the most effective treatment for respiratory bacterial
infections due to the increasing relevance of drug bioavailability. Drug delivery systems …
infections due to the increasing relevance of drug bioavailability. Drug delivery systems …
Multimodal role of amino acids in microbial control and drug development
M Idrees, AR Mohammad, N Karodia, A Rahman - Antibiotics, 2020 - mdpi.com
Amino acids are ubiquitous vital biomolecules found in all kinds of living organisms
including those in the microbial world. They are utilised as nutrients and control many …
including those in the microbial world. They are utilised as nutrients and control many …
[PDF][PDF] Archive of SID. ir
We [1, 2] and others [3- 5] have been interested in designing and making new molecules
that have biological activities, medicinal uses, coordination behaviors [6- 8] and studying …
that have biological activities, medicinal uses, coordination behaviors [6- 8] and studying …
Bioactive protein hydrolysates in the functional food ingredient industry: Overcoming current challenges
Meat proteins and associated by-products can be used as a source of bioactive hydrolysates
and peptides with potential for use as functional food ingredients. Functional foods are foods …
and peptides with potential for use as functional food ingredients. Functional foods are foods …
Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS …
The global outbreak of the COVID-19 pandemic provokes scientists to make a prompt
development of new effective therapeutic interventions for the battle against SARS-CoV-2. A …
development of new effective therapeutic interventions for the battle against SARS-CoV-2. A …
Deep eutectic solvents and pharmaceuticals
Definition Deep eutectic solvents (DES) are eutectic mixtures that present a deviation from
the ideal thermodynamic solid–liquid phase behavior, where a significant depression in the …
the ideal thermodynamic solid–liquid phase behavior, where a significant depression in the …
Cannabidiol aqueous solubility enhancement: Comparison of three amorphous formulations strategies using different type of polymers
N Koch, O Jennotte, Y Gasparrini… - International Journal of …, 2020 - Elsevier
Poor aqueous solubility of terpenophenolic compound Cannabidiol (CBD) is a major issue
in the widespread use of this promising therapeutic polyphenol. Moreover, choosing the …
in the widespread use of this promising therapeutic polyphenol. Moreover, choosing the …
[HTML][HTML] PaccMannRL: De novo generation of hit-like anticancer molecules from transcriptomic data via reinforcement learning
With the advent of deep generative models in computational chemistry, in-silico drug design
is undergoing an unprecedented transformation. Although deep learning approaches have …
is undergoing an unprecedented transformation. Although deep learning approaches have …
Polymeric micelles for multi-drug delivery in cancer
Drug combinations are common in cancer treatment and are rapidly evolving, moving
beyond chemotherapy combinations to combinations of signal transduction inhibitors. For …
beyond chemotherapy combinations to combinations of signal transduction inhibitors. For …
Metal Complexes in Target‐Specific Anticancer Therapy: Recent Trends and Challenges
Cancer is characterized by abnormal cell differentiation in or on the part of the body. The
most commonly used chemotherapeutic drugs are developed to target rapidly dividing cells …
most commonly used chemotherapeutic drugs are developed to target rapidly dividing cells …