I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Chronic inflammatory airway diseases, including asthma, chronic rhinosinusitis, eosinophilic
COPD and allergic rhinitis are a global health concern. Despite the coexistence of these …

Background Eosinophilic inflammation has been implicated in the pathogenesis, severity,
and treatment responsiveness of chronic rhinosinusitis with nasal polyps (CRSwNP) …

Contributing Authors Isam Alobid, MD, PhD1, Nithin D. Adappa, MD2, Henry P. Barham,
MD3, Thiago Bezerra, MD4, Nadieska Caballero, MD5, Eugene G. Chang, MD6, Gaurav …

Background Aspirin-exacerbated respiratory disease (AERD) is manifested by adult-onset
asthma, nasal polyposis, chronic rhinosinusitis, and aspirin sensitivity. Previously reported …

Background Chronic rhinosinusitis (CRS) is a common disorder associated with other
respiratory tract diseases such as asthma and inhalant allergy. However, the prevalence of …

Objectives We conducted a systematic literature review (SLR) to determine the
epidemiology and clinical burden of chronic rhinosinusitis with nasal polyps (CRSwNP) and …

Nasal polyps (NP) are lesions on the nasal and paranasal sinus mucosa and are a risk
factor for chronic rhinosinusitis (CRS). We performed genome-wide association studies on …

Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) often have coexisting
asthma under the concept of “United Airway Disease”, being the combination of both …

Background Chronic rhinosinusitis (CRS) and asthma describe inflammation of the upper
and lower airway, respectively. Not surprisingly, the prevalence of CRS and asthma has …