The mitochondrial proteome comprises~ 1000 (yeast)–1500 (human) different proteins,
which are distributed into four different subcompartments. The sublocalization of these …

The terminal enzyme of the mitochondrial respiratory chain, cytochrome oxidase, transfers
electrons to molecular oxygen, generating water. Within the inner mitochondrial membrane …

We report that Rcf1 (formerly Aim31), a member of the conserved hypoxia-induced gene 1
(Hig1) protein family, represents a novel component of the yeast cytochrome bc 1 …

MicroRNAs (miRNAs) are small non-coding RNAs, which inhibit the stability and/or
translation of a mRNA. miRNAs have been found to play a powerful role in various …

Synapses are the regions of the neuron that enable the transmission and propagation of
action potentials on the cost of high energy consumption and elevated demand for …

Complex III (CIII) deficiency is one of the least common oxidative phosphorylation defects
associated to mitochondrial disease. CIII constitutes the center of the mitochondrial …

The intermembrane space (IMS) represents the smallest subcompartment of mitochondria.
Nevertheless, it plays important roles in the transport and modification of proteins, lipids, and …

Aneuploidy is linked to myriad diseases but also facilitates organismal evolution. It remains
unclear how cells overcome the deleterious effects of aneuploidy until new phenotypes …

Mitochondria contain their own genome which codes for a small number of proteins. Most
mitochondrial translation products are part of the membrane-embedded reaction centers of …

Mitochondria are multifunctional metabolic factories and integrative signaling organelles of
eukaryotic cells. The structural basis for their numerous functions is a complex and dynamic …