[HTML][HTML] Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA
P Wu, Y Mo, M Peng, T Tang, Y Zhong, X Deng… - Molecular cancer, 2020 - Springer
Non-coding RNAs do not encode proteins and regulate various oncological processes. They
are also important potential cancer diagnostic and prognostic biomarkers. Bioinformatics …
are also important potential cancer diagnostic and prognostic biomarkers. Bioinformatics …
[HTML][HTML] Understanding Alzheimer disease at the interface between genetics and transcriptomics
J Verheijen, K Sleegers - Trends in Genetics, 2018 - cell.com
Over 25 genes are known to affect the risk of developing Alzheimer disease (AD), the most
common neurodegenerative dementia. However, mechanistic insights and improved …
common neurodegenerative dementia. However, mechanistic insights and improved …
The landscape of tolerated genetic variation in humans and primates
H Gao, T Hamp, J Ede, JG Schraiber, J McRae… - Science, 2023 - science.org
Personalized genome sequencing has revealed millions of genetic differences between
individuals, but our understanding of their clinical relevance remains largely incomplete. To …
individuals, but our understanding of their clinical relevance remains largely incomplete. To …
The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
A Buniello, JAL MacArthur, M Cerezo… - Nucleic acids …, 2019 - academic.oup.com
The GWAS Catalog delivers a high-quality curated collection of all published genome-wide
association studies enabling investigations to identify causal variants, understand disease …
association studies enabling investigations to identify causal variants, understand disease …
The UCSC genome browser database: 2018 update
Abstract The UCSC Genome Browser (https://genome. ucsc. edu) provides a web interface
for exploring annotated genome assemblies. The assemblies and annotation tracks are …
for exploring annotated genome assemblies. The assemblies and annotation tracks are …
[PDF][PDF] Alternative 3′ UTRs modify the localization, regulatory potential, stability, and plasticity of mRNAs in neuronal compartments
Neurons localize mRNAs near synapses where their translation can be regulated by
synaptic demand and activity. Differences in the 3′ UTRs of mRNAs can change their …
synaptic demand and activity. Differences in the 3′ UTRs of mRNAs can change their …
The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease
A multitude of factors contribute to complex diseases and can be measured with 'omics'
methods. Databases facilitate data interpretation for underlying mechanisms. Here, we …
methods. Databases facilitate data interpretation for underlying mechanisms. Here, we …
[HTML][HTML] Evolution of neuronal cell classes and types in the vertebrate retina
The basic plan of the retina is conserved across vertebrates, yet species differ profoundly in
their visual needs. Retinal cell types may have evolved to accommodate these varied needs …
their visual needs. Retinal cell types may have evolved to accommodate these varied needs …
A high-coverage Neandertal genome from Chagyrskaya Cave
F Mafessoni, S Grote, C De Filippo… - Proceedings of the …, 2020 - National Acad Sciences
We sequenced the genome of a Neandertal from Chagyrskaya Cave in the Altai Mountains,
Russia, to 27-fold genomic coverage. We show that this Neandertal was a female and that …
Russia, to 27-fold genomic coverage. We show that this Neandertal was a female and that …
RMBase v2. 0: deciphering the map of RNA modifications from epitranscriptome sequencing data
More than 100 distinct chemical modifications to RNA have been characterized so far.
However, the prevalence, mechanisms and functions of various RNA modifications remain …
However, the prevalence, mechanisms and functions of various RNA modifications remain …