Long non-coding RNAs in lung cancer: Unraveling the molecular modulators of MAPK signaling

MS Hussain, O Afzal, G Kumar, ASA Altamimi… - … -Research and Practice, 2023 - Elsevier
Lung cancer (LC) continues to pose a significant global medical burden, necessitating a
comprehensive understanding of its molecular foundations to establish effective treatment …

Exploring the role of lncrna neat1 knockdown in regulating apoptosis across multiple cancer types: A review

MS Hussain, G Gupta, M Afzal, SM Alqahtani… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators of gene expression,
contributing significantly to a diverse range of cellular processes, including apoptosis. One …

Long non-coding RNA NEAT1: a novel target for diagnosis and therapy in human tumors

P Dong, Y Xiong, J Yue, SJB Hanley… - Frontiers in …, 2018 - frontiersin.org
The nuclear paraspeckle assembly transcript 1 (NEAT1, a long non-coding RNA) is
frequently overexpressed in human tumors, and higher NEAT1 expression is correlated with …

Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation

X Liu, Y Liang, R Song, G Yang, J Han, Y Lan, S Pan… - Molecular cancer, 2018 - Springer
Background Abnormal metabolism, including abnormal lipid metabolism, is a hallmark of
cancer cells. Some studies have demonstrated that the lipogenic pathway might promote the …

Long non-coding RNA NEAT1 promotes colorectal cancer progression by competitively binding miR-34a with SIRT1 and enhancing the Wnt/β-catenin signaling …

Y Luo, JJ Chen, Q Lv, J Qin, YZ Huang, MH Yu… - Cancer letters, 2019 - Elsevier
In recent years, accumulating evidence has indicated that long non-coding RNAs (lncRNAs)
are powerful factors influencing the progression of multiple malignancies. Although a …

[HTML][HTML] Novel biomarkers for the diagnosis and prognosis of colorectal cancer

HH Oh, YE Joo - Intestinal research, 2020 - synapse.koreamed.org
Colorectal cancer (CRC) is among the most common malignancies and remains a major
cause of cancer-related death worldwide. Despite recent advances in surgical and …

The various regulatory functions of long noncoding RNAs in apoptosis, cell cycle, and cellular senescence

M Heydarnezhad Asl… - Journal of cellular …, 2022 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a group of noncoding cellular RNAs involved in
significant biological phenomena such as differentiation, cell development, genomic …

Emerging roles for lncRNA-NEAT1 in colorectal cancer

S Azizidoost, F Ghaedrahmati, O Anbiyaee… - Cancer cell …, 2022 - Springer
Colorectal cancer (CRC) is the third cause of cancer death in the world that arises from the
glandular and epithelial cells of the large intestine, during a series of genetic or epigenetic …

Interactions among lncRNAs, miRNAs and mRNA in colorectal cancer

XJ Tang, W Wang, SS Hann - Biochimie, 2019 - Elsevier
Long non-coding RNAs (lncRNAs) are longer than 200 nts non-coding transcripts and have
recently emerged as one of the largest and significantly diverse RNA families whereas …

Inhibition of lncRNA NEAT1 suppresses the inflammatory response in IBD by modulating the intestinal epithelial barrier and by exosome-mediated polarization of …

R Liu, A Tang, X Wang, X Chen… - International …, 2018 - spandidos-publications.com
Inflammatory bowel disease (IBD) is a multifactorial inflammatory disease, and increasing
evidence has demonstrated that the mechanism of the pathogenesis of IBD is associated …