The precursor of most cutaneous invasive squamous cell carcinomas (iSCC s) is
intraepithelial UV‐induced damage, known as field cancerization, which can eventually …

Simple Summary Carcinogens, causes of cancer, are usually invisible and therefore in vivo
carcinogenesis is difficult to detect. Tumor viruses, definitive carcinogens, are also usually …

Background Progression from actinic keratosis (AK) to invasive squamous cell carcinoma
(iSCC) of the skin is thought to occur after the development of full thickness epidermal …

Purpose: Oral leukoplakia is the most common oral potentially malignant disorder with an
annual malignant transformation rate of 1% to 5%. Consequently, oral leukoplakia patients …

Objectives Numerous clinical and histopathological characteristics have been associated
with malignant transformation (MT) of oral leukoplakia (OL), including classic and …

Vulvar cancer is a relatively rare gynecologic malignancy with an annual incidence in
developed countries of approximately 2 per 100,000 women. Vulvar squamous cell …

Cervical carcinoma remains one of the most common cancers affecting women worldwide,
despite effective screening programs being implemented in many countries for several …

Background Vulvar cancer and vaginal cancer are relatively rare tumors, and there had
been no established treatment principles or guidelines to treat these rare tumors in Japan …

Differentiated vulvar intrapeithelial neoplasia (dVIN) is an human papillomavirus (HPV)–
independent precursor of squamous cell carcinoma (SCC), and the aim of this study was to …

Oral leukoplakia is the most common oral potentially malignant disorder with a malignant
transformation rate into oral squamous cell carcinoma of 1–3% annually. The presence and …