Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Most of the cytotoxic chemotherapeutic agents have poor aqueous solubility. These
molecules are associated with poor physicochemical and biopharmaceutical properties …

The poor oral bioavailability arising from poor aqueous solubility should make drug research
and development more difficult. Various approaches have been developed with a focus on …

Objectives Drug pipelines are becoming increasingly difficult to formulate. This is punctuated
by both retrospective and prospective analyses that show that while 40% of currently …

Although native and modified cyclodextrins (CDs) are somewhat effective in environmental
applications, there is a continued interest in understanding their distinct role in various …

Formononetin, a naturally occurring isoflavone exhibits a wide range of therapeutic
applications including antioxidant, anti-tumor, antiviral, anti-diabetic and neuroprotective …

Cyclodextrins (CDs) are edible and biocompatible natural cyclic compounds that can
encapsulate essential oils, flavours, volatile aroma compounds, and other substances …

Cyclodextrins are a family of cyclic oligosaccharides composed of α-(1, 4) linked
glucopyranose subunits. Cyclodextrins are useful molecular chelating agents. They possess …

Cyclodextrins are cyclic oligomers of glucose that can form water-soluble inclusion
complexes with small molecules and portions of large compounds. These biocompatible …

Cyclodextrins are useful functional excipients that have enjoyed widespread attention and
use. The basis for this popularity from a pharmaceutical standpoint, is the ability of these …