Attention‐deficit hyperactivity disorder (ADHD) is the most common cognitive and
behavioural disorder diagnosed among school children. It is characterized by deficient …

OBJECTIVE: To review evidence for the neurodevelopmental effects of in utero exposure to
nicotine. Concerns about long-term cognitive and behavioral effects of prenatal exposure to …

The action of thyroid hormones (THs) in the brain is strictly regulated, since these hormones
play a crucial role in the development and physiological functioning of the central nervous …

Neuronal microtubules support intracellular transport, facilitate axon growth, and form a
basis for neuronal morphology. While microtubules in nonneuronal cells are depolymerized …

Clinical studies indicate the predominance of psychosocial factors (nurturing environment)
in the genesis of the Maternal Deprivation Syndrome. Consequences of disrupting mother …

Parkinson's disease (PD) is a neurological disorder marked by the presence of cytoplasmic
inclusions, Lewy bodies (LBs) and Lewy neurites (LNs) as well as the degeneration of …

Elevation of cAMP can overcome myelin inhibitors to encourage regeneration of the CNS.
We show that a consequence of elevated cAMP is the synthesis of polyamines, resulting …

Aliphatic polyamines are a family of polycationic molecules derived from decarboxylation of
the amino acid ornithine that classically comprise three molecules: putrescine, spermidine …

The cellular polyamines putrescine, spermidine, and spermine accelerate the aggregation
and fibrillization of α-synuclein, the major protein component of Lewy bodies associated with …

The brain is a well-organized, yet highly complex, organ in the mammalian system. Most
investigators use the whole brain, instead of a selected brain region (s), for biochemical …