Estudios bioinformáticos de la enzima convertidora de angiotensina en humanos (hACE2) para el desarrollo de posibles inhibidores contra el SARS-CoV-2
JJ Hoyos Caicedo - 2021 - repositorio.uta.edu.ec
The bioinformatic studies carried out on human angiotensin converting enzyme 2 (hACE2)
for the development of possible inhibitors against the SARS-CoV-2 virus, were mainly joint …
for the development of possible inhibitors against the SARS-CoV-2 virus, were mainly joint …
[PDF][PDF] The role of aromatic stacking in drug-drug interactions
AS Woods - Neurosci Chron, 2021 - probiologists.com
Having studied and worked in the fields of pharmacology and structural biology my first
reaction to reading an article or attending a lecture about a class of chemical compounds or …
reaction to reading an article or attending a lecture about a class of chemical compounds or …
Synthesis of sulfonamide chalcones as?-glucosidase inhibitors
IP Sukanadi - 2020 - digital.car.chula.ac.th
Diabetes mellitus occurs from deficiencies in insulin secretion or insulin resistance which
leads over time to high risk for long-term macro-and microvascular complications. Diabetes …
leads over time to high risk for long-term macro-and microvascular complications. Diabetes …
[图书][B] Functionalized Nanoscale Materials for Protein Biomarker Detection
Y Zhang - 2020 - search.proquest.com
Proteins are vital biomolecules in living organisms which function as the working element for
many aspects of life. An abnormal expression of proteins or expression of unique proteins is …
many aspects of life. An abnormal expression of proteins or expression of unique proteins is …
Structural basis of recruitment of RBM39 to DCAF15 by a sulfonamide molecular glue E7820
X Du, O Volkov, R Czerwinski, HL Tan, C Huerta… - bioRxiv, 2019 - biorxiv.org
E7820 and indisulam are two examples of aryl sulfonamides that recruit RBM39 to Rbx-Cul4-
DDA1-DDB1-DCAF15 E3 ligase complex, leading to its ubiquitination and degradation by …
DDA1-DDB1-DCAF15 E3 ligase complex, leading to its ubiquitination and degradation by …
[PDF][PDF] Research Article Computational Evaluation of the Inhibition Efficacies of HIV Antivirals on SARS-CoV-2 (COVID-19) Protease and Identification of 3D …
VP Raphael, SK Shanmughan - 2020 - academia.edu
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the novel coronavirus
behind the fast-spreading coronavirus disease 2019 (COVID-19). Pharmaceutical …
behind the fast-spreading coronavirus disease 2019 (COVID-19). Pharmaceutical …
Analysing the effect caused by increasing the molecular volume in M1-AChR receptor agonists and antagonists: a structural and computational study
W Montejo-López, R Sampieri-Cabrera… - RSC …, 2024 - pubs.rsc.org
M1 muscarinic acetylcholine receptor (M1-AChR), a member of the G protein-coupled
receptors (GPCR) family, plays a crucial role in learning and memory, making it an important …
receptors (GPCR) family, plays a crucial role in learning and memory, making it an important …
High-throughput prediction and analysis of drug-protein interactions in the druggable human proteome
C Wang - 2018 - scholarscompass.vcu.edu
Drugs exert their (therapeutic) effects via molecular-level interactions with proteins and other
biomolecules. Computational prediction of drug-protein interactions plays a significant role …
biomolecules. Computational prediction of drug-protein interactions plays a significant role …
[PDF][PDF] A Virtual Screen for Protein Targets: Elucidating Druggability in the Human Proteome with eFindsite
O Kana - 2018 - repository.lsu.edu
Identifying the viability of protein targets is one of the preliminary steps of drug discovery.
Determining the ability for a drug to bind to a protein, termed druggability, requires a …
Determining the ability for a drug to bind to a protein, termed druggability, requires a …