Virtual screening identification of novel chemical inhibitors for aberrant interactions between pathogenic mutant SOD1 and tubulin
K Hirayama, Y Fujiwara, T Terada, K Shimizu… - Neurochemistry …, 2019 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease caused by
selective motor neuron death. Mutations in the gene encoding copper/zinc superoxide …
selective motor neuron death. Mutations in the gene encoding copper/zinc superoxide …
Comprehensive Analysis and Large-Scale Screening of Binding Interactions Between PFAS and Their Mixtures with Nuclear Receptors
S Roy, K Danasekaran, J Moran, K O'Brien… - 2024 - preprints.org
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are persistent environmental
contaminants of emerging concern, recognized for their toxicity and potential carcinogenic …
contaminants of emerging concern, recognized for their toxicity and potential carcinogenic …
[引用][C] Development of novel analgesics: targeting the RNA-binding protein HuR
BP Joseph - 2024 - Dissertation, RWTH Aachen …
Exploring the therapeutic potential of cinnamon and clove essential oils for mitigating foodborne diseases: bioactivity and molecular interactions
Foodborne diseases remain a global concern due to their widespread impact on public
health. Contaminated food can lead to outbreaks of illness that affect millions of people each …
health. Contaminated food can lead to outbreaks of illness that affect millions of people each …
[PDF][PDF] RSC Chemical Biology
XZ Zhao - 2023 - pdfs.semanticscholar.org
Tyrosyl-DNA phosphodiesterase 1 (TDP1) is a member of the phospholipase D family that
can downregulate the anticancer effects of the type I topoisomerase (TOP1) inhibitors by …
can downregulate the anticancer effects of the type I topoisomerase (TOP1) inhibitors by …
Visual-analytics-driven bioinformatics methods for the analysis of biomolecular data
S Kaur - 2022 - unsworks.unsw.edu.au
Continuous technological advances in molecular biology data collection, leading to the
accumulation of large amounts of diverse data, necessitate the need for novel and …
accumulation of large amounts of diverse data, necessitate the need for novel and …
Correlation of binding site properties with chemistries used for generation of ultra-large virtual libraries.
R Song, M Nicklaus, N Tarasova - 2023 - chemrxiv.org
Although the size of virtual libraries of synthesizable compounds is growing rapidly, we are
still enumerating only tiny fractions of the drug-like chemical universe. At the same time, our …
still enumerating only tiny fractions of the drug-like chemical universe. At the same time, our …
[引用][C] Siyuan Song1, 2, 3, Jiayu Zhou1, 2, 3, Ye Li1, 2, 3, Jiatong Liu1, 2, Jingzhan Li1, 2, 3 & Peng Shu1, 2, 3Ε
ARA Radix, AFA Fructus, DL Drug-likeness - Scientific Reports, 2022
Identificación de posibles dianas terapéuticas en Alzheimer utilizando pipeline bioinformático combinado para aplicarlas al diseño de fármacos asistidos por …
LL Barriga Sanchez - 2023 - repositorio.uta.edu.ec
El acoplamiento molecular demostró que Estradiol y Tricostatina A pueden generar una
inhibición de la proteína CCND1, mientras que Dorsomorfina induce la inhibición de CDK6 …
inhibición de la proteína CCND1, mientras que Dorsomorfina induce la inhibición de CDK6 …
[PDF][PDF] Design of Novel Selective Estrogen Receptor Inhibitors using Molecular Docking and Protein-Ligand Interaction Fingerprint Studies
G Rajitha, MV Rani, UN Vankadoth, A Umamaheswari - 2021 - researchgate.net
Aims: The genomic and non-genomic actions of human estrogen receptor α (hERα) play a
crucial role in breast epithelial cell proliferation and survival, as well as mammary …
crucial role in breast epithelial cell proliferation and survival, as well as mammary …