[PDF][PDF] Modification of peptides for improved membrane permeability and side chain diversity

OJN Openy - 2023 - eldorado.tu-dortmund.de
The four-year journey abroad in pursuing a Dr. rer. nat. has been incredibly enriching on
both academic and personal fronts. It would not have been possible without the support and …

Synthesis and Structure-Activity Relationship Studies of 3-(N-Butylethanimidoyl)-4-hydroxy-2H-chromen-2-one (BHC) Analogues for Myosin II Inhibition

J Brawley - 2022 - search.proquest.com
The objective of current treatments for various myopathies is to interrupt the signal from the
brain to the affected muscle group, providing relief. To prevent unwanted side effects and …

Disminución de glutatión reducido en ratas Wistar machos tras la exposición a naftaleno

I Olaoye, A Awotula, B Oso, O Agboola… - Biotecnología …, 2022 - medigraphic.com
En el estudio se evaluó los posibles efectos de la exposición al naftaleno (GSH) mediante
abordajes in vivo e in silico. En el estudio in vivo se evaluó los niveles de glutatión en 24 …

[PDF][PDF] Biochemical and Biophysical Approaches to Protein Ligand and Enzyme Inhibitor Discovery

E Antony - 2022 - researchspace.auckland.ac.nz
At any given point in time, a myriad of reactions occurs in a living cell. These reactions often
serve a specific purpose and are more often than not, co-ordinated by proteins and …

Structural analysis of UBA5 and its binding partners

S Fuchs - 2022 - ediss.sub.uni-hamburg.de
The focus of this work was the analysis of the activation cascade, which activates the
ubiquitin-like protein Ubiquitin Fold Modifier 1 (UFM1). Proteins involved in this cascade are …

2, 5-Bis (2, 2, 2-trifluoroethoxy) phenyl-tethered 1, 3, 4-Oxadiazoles Derivatives: Synthesis, In Silico Studies, and Biological Assessment as Potential Candidates for …

SD Shankara, AM Isloor, AK Kudva, SV Raghu… - Molecules, 2022 - mdpi.com
In the present work, a series of new 1-{5-[2, 5-bis (2, 2, 2-trifluoroethoxy) phenyl]-1, 3, 4-
oxadiazol-3-acetyl-2-aryl-2H/methyl derivatives were synthesized through a multistep …

Collaborative Filtering based Generative Networks

R Srinivas - 2021 - scholar.smu.edu
Collaborative Filtering, a popular method for recommendation engines, models its
predictions using past interactions between the entities in question (aka users/movies or …

Designing an optmized met X/Y enzymes for an efficient methionine production in E. coli

L Rodrigues - 2022 - diva-portal.org
Methionine is a proteinogenic amino acid critical amino for the pharmaceutical,
biotechnological and agricultural industries. The overall methionine biosynthetic pathway is …

[HTML][HTML] Molecular docking and molecular dynamics study of 3-hydroxybutyrate

A Asnawi, E Febrina, W Aligita, LO Aman, F Razi - jppres.com
Abstract Context: Molecularly imprinted polymers (MIPs) are promising materials with
tailored binding sites that can selectively recognize and bind target molecules. The …

[PDF][PDF] Novel coumarin derivatives as potential HDAC2 inhibitors : in silico study.

P Dhakla, R Dutt, D Rani - 2022 - agribiop.com
Designing of selective HDAC2 inhibitors will have less adverse effects and better safety
profiles. For HDAC2 selectivity, the coumarin derivatives were designed according to the …