Glycans linked to proteins and lipids play key roles in biology; thus, accurate replication of
cellular glycans is crucial for maintaining function following cell division. The fact that …

Cellular glycome assembly requires the coordinated action of a large number of
glycosyltransferases that catalyse the transfer of a sugar residue from a donor to specific …

Glycosyltransferases (GTs) are ubiquitous in nature and are required for the transfer of
sugars to a variety of important biomolecules. This essential enzyme family has been a focus …

Glycosyltransferases (GTs) are prevalent across the tree of life and regulate nearly all
aspects of cellular functions. The evolutionary basis for their complex and diverse modes of …

The β-1, 4-galactosyltransferase 7 (β4GalT7) enzyme is involved in proteoglycan synthesis.
In the presence of a manganese ion, it transfers galactose from UDP-galactose to xylose on …

β-1, 4-Galactosyltransferase 7 (β4GalT7) is an essential enzyme in the biosynthesis of
glycosaminoglycan (GAG) chains of proteoglycans (PGs). Mammalian cells produce PGs …

The economically important seaweed Gracilariopsis lemaneiformis (Gp. lemaneiformis) is
the main resource for agar production and abalone bait. Few studies have focused on the …

β1, 4-Galactosyltransferase 7 (β4GalT7) is a key enzyme initiating glycosaminoglycan
(GAG) synthesis. Based on in vitro and ex vivo kinetics studies and structure-based …

Among glycosaminoglycan (GAG) biosynthetic enzymes, the human β1, 4-
galactosyltransferase 7 (hβ4GalT7) is characterized by its unique capacity to take over …

Silkworm Bombyx mori is one of the insect hosts for recombinant protein production at
academic and industrial levels. B. mori and other insect cells can produce mammalian …