Bioinert high performance ceramics exhibit detrimental features for implant components with
direct bone contact because of their low osseointegrating capability. We hypothesized that …

Micro/nano-textured titanium surface topography promotes osteoblast differentiation and the
Wnt/β-catenin signaling pathway. However, the response of rat bone mesenchymal stem …

The antibacterial properties of the microarc oxidation coating have gained wide attentions,
and W-containing surface has been verified to be notably bactericidal. Herein, in this work …

Direct laser machining and electrospinning are utilized to obtain a bi‐layered hybrid scaffold
with hierarchical topographical features to mimic extracellular matrix‐like microenvironment …

The extracellular environment possesses a rich milieu of biophysical and biochemical
signaling cues that are simultaneously integrated by cells and influence cellular phenotype …

A wide variety of cell types exhibit substrate topography-based behavior, also known as
contact guidance. However, the precise cellular mechanisms underlying this process are still …

Antibacterial agents derived from conventional organic compounds have traditionally been
employed as a biofilm protective coating for many years. These agents, on the other hand …

Formation of thin films on titanium alloys incorporating bioactive small molecules or
macromolecules is a route to improve their biocompatibility. Aminoalkylsilanes are …

Titanium substrates with micro/nano hierarchical features could positively mediate the
osteogenesis of a titanium implant; nevertheless, the underlying molecular mechanism …

Cells reside in a complex microenvironment in situ, with a number of chemical and physical
parameters interacting to modulate cell phenotype and activities. To understand cell …