Surface fluid registration of conformal representation: Application to detect disease burden and genetic influence on hippocampus

J Shi, PM Thompson, B Gutman, Y Wang… - NeuroImage, 2013 - Elsevier
In this paper, we develop a new automated surface registration system based on surface
conformal parameterization by holomorphic 1-forms, inverse consistent surface fluid …

Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study

RJ Dawe, DA Bennett, JA Schneider, K Arfanakis - PloS one, 2011 - journals.plos.org
The volume of the hippocampus measured with structural magnetic resonance imaging
(MRI) is increasingly used as a biomarker for Alzheimer's disease (AD). However, the …

Regional hippocampal damage in heart failure

MA Woo, JA Ogren, CM Abouzeid… - European journal of …, 2015 - Wiley Online Library
Aims Heart failure (HF) patients show cognitive and mood impairments, including short‐term
memory loss and depression, that have an adverse impacting on quality of life and self‐care …

Voxel and surface-based topography of memory and executive deficits in mild cognitive impairment and Alzheimer's disease

K Nho, SL Risacher, PK Crane, C DeCarli… - Brain imaging and …, 2012 - Springer
Mild cognitive impairment (MCI) and Alzheimer's disease (AD) are associated with a
progressive loss of cognitive abilities. In the present report, we assessed the relationship of …

Genetic influence of apolipoprotein E4 genotype on hippocampal morphometry: An N = 725 surface‐based Alzheimer's disease neuroimaging initiative study

J Shi, N Lepore, BA Gutman… - Human brain …, 2014 - Wiley Online Library
The apolipoprotein E (APOE) e4 allele is the most prevalent genetic risk factor for
Alzheimer's disease (AD). Hippocampal volumes are generally smaller in AD patients …

The unique alterations of hippocampus and cognitive impairment in chronic obstructive pulmonary disease

J Li, GH Fei - Respiratory research, 2013 - Springer
Background Cognitive impairment has been found in chronic obstructive pulmonary disease
(COPD) patients. However, the structural alteration of the brain and underlying mechanisms …

Hippocampal and ventricular changes in Parkinson's disease mild cognitive impairment

L Apostolova, G Alves, KS Hwang, S Babakchanian… - Neurobiology of …, 2012 - Elsevier
We analyzed T1-weighted brain magnetic resonance imaging data of 100 cognitively normal
elderly controls (NC), 127 cognitively normal Parkinson's disease (PD; PDCN) and 31 PD …

Comparing 3T and 1.5 T MRI for mapping hippocampal atrophy in the Alzheimer's Disease Neuroimaging Initiative

N Chow, KS Hwang, S Hurtz… - American Journal …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Prior MR imaging studies, primarily at 1.5 T, established
hippocampal atrophy as a biomarker for Alzheimer disease. 3T MR imaging offers a higher …

The role of the major histocompatibility complex region in cognition and brain structure: a schizophrenia GWAS follow-up

JTR Walters, D Rujescu, B Franke… - American journal of …, 2013 - Am Psychiatric Assoc
Objective The authors investigated the effects of recently identified genome-wide significant
schizophrenia genetic risk variants on cognition and brain structure. Method A panel of six …

Applying surface-based hippocampal morphometry to study APOE-E4 allele dose effects in cognitively unimpaired subjects

Q Dong, W Zhang, J Wu, B Li, EH Schron… - NeuroImage: Clinical, 2019 - Elsevier
Apolipoprotein E (APOE) e4 is the major genetic risk factor for late-onset Alzheimer's
disease (AD). The dose-dependent impact of this allele on hippocampal volumes has been …