Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Bioactive inorganic nanomaterials for cancer theranostics

Z Pei, H Lei, L Cheng - Chemical Society Reviews, 2023 - pubs.rsc.org
Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

Supramolecular photosensitizer enables oxygen-independent generation of hydroxyl radicals for photodynamic therapy

KX Teng, LY Niu, QZ Yang - Journal of the American Chemical …, 2023 - ACS Publications
The highly oxygen-dependent nature of photodynamic therapy (PDT) limits its therapeutic
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …

Current and promising applications of Hf (IV)-based MOFs in clinical cancer therapy

X Chen, M Li, M Lin, C Lu, A Kumar, Y Pan… - Journal of Materials …, 2023 - pubs.rsc.org
Cancer is one of the greatest challenges in medical science today as it poses a serious
threat to human life. In view of this, myriad of therapeutic strategies are being developed for …

[HTML][HTML] Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy

J Yang, D Dai, X Zhang, L Teng, L Ma, YW Yang - Theranostics, 2023 - ncbi.nlm.nih.gov
Cancer remains a severe threat to human health. To date, although various therapeutic
methods, including radiotherapy (RT), chemotherapy, chemodynamic therapy (CDT) …

Engineering of BODIPY-based theranostics for cancer therapy

Z Mao, JH Kim, J Lee, H Xiong, F Zhang… - Coordination Chemistry …, 2023 - Elsevier
In recent years, BODIPY-based theranostics have increasingly been used in cancer therapy
and have achieved significant success. According to photochemical theories, the optical …

Latest developments in metal complexes as anticancer agents

R Paprocka, M Wiese-Szadkowska… - Coordination Chemistry …, 2022 - Elsevier
Every year novel biologically active compounds are designed as antitumor agents. This
review covers and highlights some of the most important findings described during 2018 …

Multifunctional nanotheranostics for near infrared optical imaging-guided treatment of brain tumors

L Zhang, Y Liu, H Huang, H Xie, B Zhang, W Xia… - Advanced drug delivery …, 2022 - Elsevier
Malignant brain tumors, a heterogeneous group of primary and metastatic neoplasms in the
central nervous system (CNS), are notorious for their highly invasive and devastating …

A Highly Water‐Soluble Aggregation‐Induced Emission Luminogen with Anion‐π+ Interactions for Targeted NIR Imaging of Cancer Cells and Type I Photodynamic …

L Liu, C Li, J Gong, Y Zhang, W Ji, L Feng… - Angewandte …, 2023 - Wiley Online Library
The low oxygen dependence of type I photosensitizers (PSs) has made them a popular
choice for treating solid tumors. However, the drawbacks of poor water solubility, short …

[HTML][HTML] Supramolecular photodynamic agents for simultaneous oxidation of NADH and generation of superoxide radical

KX Teng, LY Niu, N Xie, QZ Yang - Nature Communications, 2022 - nature.com
Given that Type-I photosensitizers (PSs) have hypoxia tolerance, developing general
approaches to prepare Type-I PSs is of great importance, but remains a challenge. Here, we …