Many new chemical entities (NCEs) have been discovered with the development of the
pharmaceutical industry. However, the main disadvantage of these drugs is their low …

Since the emergence of Soluplus®(SOL) as a commercial graft copolymer, multiple
publications have been issued on its promising potential as a solubilizing excipient that …

Alectinib hydrochloride (ALH), a tyrosine kinase inhibitor, is a practically water-insoluble
drug classified as BCS class IV. The present study aimed to develop novel suspended self …

Self-emulsifying drug delivery systems (SEDDS) are a proven method for poorly soluble
substances works by increasing the solubility and bioavailability. SEDDS and isotropic …

Self-emulsifying drug delivery systems (ie SEDDS, SMEDDS and SNEDDS) are widely
employed as solubility and bioavailability enhancing formulation strategies for poorly water …

The term nanocarrier refers to sub-micrometric particles of less than 100 nm, designed to
transport, distribute, and release nanotechnology-based drug delivery systems. siRNA …

The TLR4-NLRP3 signaling pathway plays an essential role in the development of
inflammation and especially endometritis. Rosmarinic acid (RA) can have potent anti …

Micro-/nanoparticle formulations containing drugs with or without various biocompatible
excipients are widely used in the pharmaceutical field to improve the physicochemical and …

The aim of the research was to prepare & evaluate double w/o/w self-nano emulsifying drug
delivery system (SNEDDS) of imatinib mesylate (IMT) and to investigates its anticancer …

Our study aimed to develop a self-microemulsifying drug delivery system for the poorly
aqueous-soluble drug Coenzyme Q10, to improve the dissolution and the oral …