[HTML][HTML] Long-term real-world effectiveness of allergy immunotherapy in patients with allergic rhinitis and asthma: Results from the REACT study, a retrospective cohort …

B Fritzsching, M Contoli, C Porsbjerg… - The Lancet Regional …, 2022 - thelancet.com
Background Allergen immunotherapy (AIT) is the only causal treatment for respiratory
allergy. Long-term real-life effectiveness of AIT remains to be demonstrated beyond the …

Gut microbiota and lung injury

J Tan, Y Tang, J Huang - Gut Microbiota and Pathogenesis of Organ Injury, 2020 - Springer
Gut microbiota are known to impact multiple organs including the lung. The cross talk
between gut microbes and lungs, termed as the “gut–lung axis,” is vital for immune response …

Handling of allergen immunotherapy in the COVID‐19 pandemic: an ARIA‐EAACI statement

L Klimek, M Jutel, C Akdis, J Bousquet, M Akdis… - Allergy, 2020 - Wiley Online Library
The current COVID-19 pandemic influences many areas of social life, medical treatments
and the way allergy diagnosis and treatment is performed. Allergen-specific immunotherapy …

[HTML][HTML] Single-cell and population transcriptomics reveal pan-epithelial remodeling in type 2-high asthma

ND Jackson, JL Everman, M Chioccioli, L Feriani… - Cell reports, 2020 - cell.com
The type 2 cytokine-high asthma endotype (T2H) is characterized by IL-13-driven mucus
obstruction of the airways. To further investigate this incompletely understood pathobiology …

[HTML][HTML] Risk factors for herpes zoster: should people with asthma or COPD be vaccinated?

E Safonova, BP Yawn, T Welte, C Wang - Respiratory research, 2023 - Springer
Without vaccination, an estimated 1 in 3 individuals will develop herpes zoster (HZ) in their
lifetime. Increased risk of HZ is attributed to impaired cell-mediated immunity, as observed in …

Allergen immunotherapy enhances airway epithelial antiviral immunity in patients with allergic asthma (VITAL study): a double-blind randomized controlled trial

C Woehlk, S Ramu, A Sverrild… - American Journal of …, 2023 - atsjournals.org
Rationale: Allergic asthma is linked to impaired bronchial epithelial secretion of IFNs, which
may be causally linked to the increased risk of viral exacerbations. We have previously …

Allergen immunotherapy effectively reduces the risk of exacerbations and lower respiratory tract infections in both seasonal and perennial allergic asthma: a …

C Woehlk, A Von Bülow, M Ghanizada… - European …, 2022 - Eur Respiratory Soc
Background Allergic asthma is associated with increased risk of respiratory tract infections
and exacerbations. It remains unclear whether this susceptibility is conditioned by seasonal …

[HTML][HTML] Allergen immunotherapy in the current COVID-19 pandemic: A position paper of AeDA, ARIA, EAACI, DGAKI and GPA: Position paper of the German ARIA …

L Klimek, O Pfaar, M Worm, KC Bergmann… - Allergologie …, 2020 - ncbi.nlm.nih.gov
Allergen-specific immunotherapy (AIT) is the only causal therapy with a proven long-term
benefit in allergic airway diseases, such as allergic bronchial asthma or allergic …

[HTML][HTML] Severe asthma trajectories in adults: findings from the NORDSTAR cohort

A von Bülow, S Hansen, P Sandin… - European …, 2023 - Eur Respiratory Soc
Background There is limited evidence on the pathways leading to severe asthma and we
are presently unable to effectively predict the progression of the disease. We aimed to …

House dust mite sensitization and exposure affects bronchial epithelial anti‐microbial response to viral stimuli in patients with asthma

S Cerps, A Sverrild, S Ramu, JJ Nieto‐Fontarigo… - Allergy, 2022 - Wiley Online Library
Introduction Allergen exposure worsens viral‐triggered asthma exacerbations and could
predispose the host to secondary bacterial infections. We have previously demonstrated that …