Cell origins of high-grade serous ovarian cancer

J Kim, EY Park, O Kim, JM Schilder, DM Coffey… - Cancers, 2018 - mdpi.com
High-grade serous ovarian cancer, also known as high-grade serous carcinoma (HGSC), is
the most common and deadliest type of ovarian cancer. HGSC appears to arise from the …

Guidelines to aid in the distinction of endometrial and endocervical carcinomas, and the distinction of independent primary carcinomas of the endometrium and …

CJR Stewart, CP Crum, WG McCluggage… - International Journal …, 2019 - journals.lww.com
In most cases of suspected endometrial neoplasia tumor origin can be correctly assigned
according to a combination of clinical, radiologic, and pathologic features, even when the …

Uterine serous carcinoma: Molecular features, clinical management, and new and future therapies

EK Lee, AN Fader, AD Santin, JF Liu - Gynecologic oncology, 2021 - Elsevier
Uterine serous carcinoma (USC) is an aggressive subtype of endometrial cancer.
Multimodality treatment with surgery, radiotherapy, and chemotherapy is commonly used …

Endometrial cancer and BRCA mutations: a systematic review

ML Gasparri, S Bellaminutti, AA Farooqi… - Journal of Clinical …, 2022 - mdpi.com
This systematic review identifies, evaluates, and summarises the findings of all relevant
individual studies on the prevalence of BRCA mutation (BRCAm) in endometrial cancer …

Uterine serous carcinomas frequently metastasize to the fallopian tube and can mimic serous tubal intraepithelial carcinoma

F Kommoss, A Faruqi, CB Gilks, SL Leen… - The American Journal …, 2017 - journals.lww.com
We investigated the frequency, histopathologic, and immunohistochemical characteristics of
tubal involvement in uterine serous carcinoma (USC) and aimed to clarify the relationship …

Serous tubal intraepithelial carcinoma: a concise review for the practicing pathologist and clinician

SE Bachert, A McDowell Jr, D Piecoro… - Diagnostics, 2020 - mdpi.com
Ovarian cancer is the deadliest gynecologic malignancy, accounting for more than 14,000
deaths each year. With no established way to prevent or screen for it, the vast majority of …

The many faces of serous neoplasms and related lesions of the female pelvis: a review

S Rashid, MA Arafah, M Akhtar - Advances in Anatomic Pathology, 2022 - journals.lww.com
Ovarian serous tumors and related lesions are one of the most common conditions of the
female genital tract. While ovarian high-grade serous carcinoma carries high mortality and …

PAX8 plays an essential antiapoptotic role in uterine serous papillary cancer

B Fares, L Berger, E Bangiev-Girsh, RR Kakun… - Oncogene, 2021 - nature.com
Endometrial carcinoma (EC) is the fourth-most common cancer in women in the United
States, and generally carries a favorable prognosis. However, about 10% of EC patients …

Clinical characteristics of primary Fallopian tube carcinoma: A single‐institution retrospective study of 57 cases

Z Ma, L Gao, H Li, J Li, G Zhang… - International Journal of …, 2021 - Wiley Online Library
Objective To analyze the clinical profile and prognosis of primary Fallopian tube cancer
(PFTC) in order to improve earlier diagnosis. Methods In this retrospective study, 57 women …

Incidental serous tubal intraepithelial carcinoma and non-neoplastic conditions of the fallopian tubes in grossly normal adnexa: a clinicopathologic study of 388 …

JD Seidman, J Krishnan, A Yemelyanova… - International Journal of …, 2016 - journals.lww.com
Serous tubal intraepithelial carcinoma (STIC), the putative precursor of the majority of
extrauterine high-grade serous carcinomas, has been reported in both high-risk women …