Elucidating glial responses to products of diabetes-associated systemic dyshomeostasis

X Zhang, F Zhang, X Xu - Clinical and Translational Medicine, 2024 - Wiley Online Library

Diabetic retinopathy (DR) is a leading cause of irreversible blindness in the working‐age
populations. Despite decades of research on the pathogenesis of DR for clinical care, a …

Natural diterpenoid EKO activates deubiqutinase ATXN3 to preserve vascular endothelial integrity and alleviate diabetic retinopathy through c-fos/focal adhesion axis

D Ge, T Luo, Y Sun, M Liu, Y Lyu, W Yin, R Li… - International Journal of …, 2024 - Elsevier

Diabetic retinopathy (DR) is one of the most prevalent severe diabetic microvascular
complications caused by hyperglycemia. Deciphering the underlying mechanism of vascular …

Alzheimer's disease as a causal risk factor for diabetic retinopathy: a Mendelian randomization study

F Ouyang, P Yuan, Y Ju, W Chen, Z Peng… - Frontiers in …, 2024 - frontiersin.org

Objectives This study aims to investigate the causal relationship between Alzheimer's
Disease (AD) and Diabetic Retinopathy (DR). Methods Employing Mendelian …

[HTML][HTML] Stem cell factor protects against chronic ischemic retinal injury by modulating on neurovascular unit

X Chen, X Liu, H He, X Guo, S Li, Y Huang… - Biomedicine & …, 2024 - Elsevier

Retinal ischemia is a significant factor in various vision-threatening diseases, but effective
treatments are currently lacking. This study explores the potential of stem cell factor (SCF) in …

Germacrone Protects against NF-κB-Mediated Inflammatory Signaling, Apoptosis, and Retinal Ganglion Cell Survival in a Rat Glaucoma Model

Y Yuan, L Shao - The Tohoku Journal of Experimental Medicine, 2024 - jstage.jst.go.jp

Retinal ischemia-reperfusion (I/R) is a pathological phenomenon that causes cellular
destruction in several ocular disorders, so there is a need for novel possible neuroprotective …