Tumor cells do not exist in isolation in vivo, and carcinogenesis depends on the surrounding
tumor microenvironment (TME), composed of a myriad of cell types and biophysical and …

Over the past millennia, life expectancy has drastically increased. While a mere 25 years
during Bronze and Iron ages, life expectancy in many European countries and in Japan is …

Colon cancer etiology involves a wide spectrum of genetic and epigenetic alterations,
finding it challenging to find effective therapeutic strategies. Quercetin exhibits potent anti …

The study of the metastatic cascade has revealed the complexity of the process and the
multiple cellular states that disseminated cancer cells must go through. The tumor …

Rather than a “short‐term tenant,” the tumor microbiome has been shown to play a vital role
as a “permanent resident,” affecting carcinogenesis, cancer development, metastasis, and …

Aging as an inevitable phenomenon is associated with pervasive changes in physiological
functions. There is a relationship between aging and the increase of several chronic …

Abstract Hexavalent chromium [Cr (VI)], a Group I carcinogen classified by the International
Agency for Research on Cancer (IARC), represents one of the most common occupational …

Aging is a complex and gradual biological process that leads to increased vulnerability to
several major human diseases. As global population aging poses significant public health …

Advancements in understanding skin aging mechanisms, which encompass both external
and internal aging processes, have spurred the development of innovative treatments …

The aim of this review is to provide an updated review of the epigenetic factors involved in
the onset and development of osteoarthritis (OA). OA is a prevalent degenerative joint …