Protein misfolding and aggregation in the brain: common pathogenetic pathways in neurodegenerative and mental disorders
A Ochneva, Y Zorkina, O Abramova, O Pavlova… - International journal of …, 2022 - mdpi.com
Mental disorders represent common brain diseases characterized by substantial
impairments of social and cognitive functions. The neurobiological causes and mechanisms …
impairments of social and cognitive functions. The neurobiological causes and mechanisms …
Therapeutic potential of exogenous ketone supplement induced ketosis in the treatment of psychiatric disorders: review of current literature
Globally, psychiatric disorders, such as anxiety disorder, bipolar disorder, schizophrenia,
depression, autism spectrum disorder, and attention-deficit/hyperactivity disorder (ADHD) …
depression, autism spectrum disorder, and attention-deficit/hyperactivity disorder (ADHD) …
Resveratrol attenuates rotenone-induced inflammation and oxidative stress via STAT1 and Nrf2/Keap1/SLC7A11 pathway in a microglia cell line
W Sun, H Li, Y Shen, H Xiao - Pathology-Research and Practice, 2021 - Elsevier
Scope Resveratrol is abundant in grapes. A protective role for resveratrol in anti-oxidation
and anti-inflammatory has been demonstrated. Rotenone is a pesticide, used to make …
and anti-inflammatory has been demonstrated. Rotenone is a pesticide, used to make …
Oxidative stress biomarkers among schizophrenia inpatients
M Więdłocha, N Zborowska, P Marcinowicz… - Brain Sciences, 2023 - mdpi.com
Background. Finding the associations between schizophrenia symptoms and the biomarkers
of inflammation, oxidative stress and the kynurenine pathway may lead to the …
of inflammation, oxidative stress and the kynurenine pathway may lead to the …
The role of hypothalamic endoplasmic reticulum stress in schizophrenia and antipsychotic-induced weight gain: A narrative review
R Zhou, M He, J Fan, R Li, Y Zuo, B Li, G Gao… - Frontiers in …, 2022 - frontiersin.org
Schizophrenia (SCZ) is a serious mental illness that affects 1% of people worldwide. SCZ is
associated with a higher risk of developing metabolic disorders such as obesity …
associated with a higher risk of developing metabolic disorders such as obesity …
Intermingling of gut microbiota with brain: Exploring the role of probiotics in battle against depressive disorders
Depression is a debilitating psychiatric ailment which exerts disastrous effects on one's
mental and physical health. Depression is accountable for augmentation of various life …
mental and physical health. Depression is accountable for augmentation of various life …
Glucose dysregulation in antipsychotic-naive first-episode psychosis: in silico exploration of gene expression signatures
J Lee, X Xue, E Au, WB McIntyre… - Translational …, 2024 - nature.com
Abstract Antipsychotic (AP)-naive first-episode psychosis (FEP) patients display early
dysglycemia, including insulin resistance and prediabetes. Metabolic dysregulation may …
dysglycemia, including insulin resistance and prediabetes. Metabolic dysregulation may …
The importance of endoplasmic reticulum stress as a novel antidepressant drug target and its potential impact on CNS disorders
M Jóźwiak-Bębenista, P Sokołowska, M Siatkowska… - Pharmaceutics, 2022 - mdpi.com
Many central nervous system (CNS) diseases, including major depressive disorder (MDD),
are underpinned by the unfolded protein response (UPR) activated under endoplasmic …
are underpinned by the unfolded protein response (UPR) activated under endoplasmic …
Identification of a diagnostic model and molecular subtypes of major depressive disorder based on endoplasmic reticulum stress-related genes
S Huang, Y Li, J Shen, W Liang, C Li - Frontiers in Psychiatry, 2023 - frontiersin.org
Subject Major depressive disorder (MDD) negatively affects patients' behaviours and daily
lives. Due to the high heterogeneity and complex pathological features of MDD, its diagnosis …
lives. Due to the high heterogeneity and complex pathological features of MDD, its diagnosis …
Cr (VI) induces crosstalk between apoptosis and autophagy through endoplasmic reticulum stress in A549 cells
H Ge, Z Li, L Jiang, Q Li, C Geng, X Yao, X Shi… - Chemico-Biological …, 2019 - Elsevier
Abstract Hexavalent chromium [Cr (VI)], which is widely found in occupational environments,
is a recognized human carcinogen. In this study, the role of endoplasmic reticulum (ER) …
is a recognized human carcinogen. In this study, the role of endoplasmic reticulum (ER) …