Chemokines in colon cancer progression
SN Jia, YB Han, R Yang, ZC Yang - Seminars in cancer biology, 2022 - Elsevier
Colon cancer is a major human cancer accounting for about a tenth of all cancer cases thus
making it among the top three cancers in terms of incidence as well as mortality. Metastasis …
making it among the top three cancers in terms of incidence as well as mortality. Metastasis …
[HTML][HTML] The role of NF-κB in breast cancer initiation, growth, metastasis, and resistance to chemotherapy
Breast cancer (BC) is the second most fatal disease and is the prime cause of cancer allied
female deaths. BC is caused by aberrant tumor suppressor genes and oncogenes regulated …
female deaths. BC is caused by aberrant tumor suppressor genes and oncogenes regulated …
[HTML][HTML] Single-cell RNA sequencing unveils the communications between malignant T and myeloid cells contributing to tumor growth and immunosuppression in …
Y Du, Y Cai, Y Lv, L Zhang, H Yang, Q Liu, M Hong… - Cancer Letters, 2022 - Elsevier
Cutaneous T cell lymphoma (CTCL) is characterized by the accumulation of malignant T
cells in the skin. However, advanced CTCL pathophysiology remains elusive and …
cells in the skin. However, advanced CTCL pathophysiology remains elusive and …
[HTML][HTML] Epigenetic regulation of CXCR4 signaling in cancer pathogenesis and progression
Signaling involving chemokine receptor CXCR4 and its ligand SDF-1/CXL12 has been
investigated for many years for its possible role in cancer progression and pathogenesis …
investigated for many years for its possible role in cancer progression and pathogenesis …
[HTML][HTML] The cross-talk between miRNAs and JAK/STAT pathway in cutaneous T cell lymphoma: Emphasis on therapeutic opportunities
K Patil, G Sher, S Kuttikrishnan, S Moton… - Seminars in Cell & …, 2022 - Elsevier
Abstract Mycosis Fungoides (MF) and Sézary Syndrome (SS) belong to a wide spectrum of T
cell lymphoproliferative disorders collectively termed cutaneous T cell lymphomas (CTCL) …
cell lymphoproliferative disorders collectively termed cutaneous T cell lymphomas (CTCL) …
Integrated transcriptome and trajectory analysis of cutaneous T-cell lymphoma identifies putative precancer populations
The incidence of cutaneous T-cell lymphoma (CTCL) increases with age, and blood
involvement portends a worse prognosis. To advance our understanding of the development …
involvement portends a worse prognosis. To advance our understanding of the development …
Cytokine/chemokine assessment as a complementary diagnostic tool for inflammatory skin diseases
TJ Liu, LL Lin, E McMeniman, J Wu, YC Kao… - Frontiers in …, 2022 - frontiersin.org
Inflammatory skin conditions are the 4th leading cause of non-fatal health burden in the
general population worldwide. The diagnosis of skin lesions due to systemic drug reactions …
general population worldwide. The diagnosis of skin lesions due to systemic drug reactions …
[HTML][HTML] Socs1-knockout in skin-resident CD4+ T cells in a protracted contact-allergic reaction results in an autonomous skin inflammation with features of early-stage …
Y Luo, MH Vermeer, S de Haan, P Kinderman… - … and Biophysics Reports, 2023 - Elsevier
Recent detailed genomic analysis of mycosis fungoides (MF) identified suppressor of
cytokine signaling 1 (SOCS1), an inhibitor of JAK/STAT signaling, as one of the frequently …
cytokine signaling 1 (SOCS1), an inhibitor of JAK/STAT signaling, as one of the frequently …
Spatially guided and single cell tools to map the microenvironment in cutaneous T-cell lymphoma
E Kalliara, E Belfrage, U Gullberg, K Drott, S Ek - Cancers, 2023 - mdpi.com
Simple Summary While most patients with cutaneous T-cell lymphoma (CTCL) may be
diagnosed with early-stage disease, approximately 25–30% of those patients will …
diagnosed with early-stage disease, approximately 25–30% of those patients will …
Unraveling the Role of the NLRP3 Inflammasome in Lymphoma: Implications in Pathogenesis and Therapeutic Strategies
IE Stergiou, C Tsironis, SP Papadakos… - International Journal of …, 2024 - mdpi.com
Inflammasomes are multimeric protein complexes, sensors of intracellular danger signals,
and crucial components of the innate immune system, with the NLRP3 inflammasome being …
and crucial components of the innate immune system, with the NLRP3 inflammasome being …