In 1985, we reported that a naturally occurring human antibody (anti-Gal), produced as the
most abundant antibody (1% of immunoglobulins) throughout the life of all individuals …

Identifying the functional roles of carbohydrates in biological systems has been an area of
intense study in recent years. Although carbohydrates were once viewed only as inert …

Tremendous advances in biocatalytic approaches to oligosaccharide synthesis have taken
place in the past two years. The use of isolated enzymes, both glycosyltransferases and …

This review describes the use of matrix‐assisted laser desorption/ionization (MALDI) mass
spectrometry for the analysis of carbohydrates and glycoconjugates and continues coverage …

Abstract Poly-N-acetyllactosamine (poly-LacNAc) structures have been identified as
important ligands for galectin-mediated cell adhesion to extra-cellular matrix (ECM) proteins …

The α-Gal trisaccharide Galα (1→ 3) Galβ (1→ 4) GlcNAc 11 was synthesized on a
homogeneously soluble polymeric support (polyethylene glycol, PEG) by use of a multi …

I. INTRODUCTION Recent demonstrations that oligosaccharides play important roles in
diverse biological events have resulted in renewed interest in the synthesis of …

Glycosyltransferases are key enzymes in glycoconjugate biosynthesis, which make them
important targets for biomedical research. Among the different methodologies developed to …

Abstract α (1, 3) Galactosyltransferase (GT) is a Golgi-localized enzyme that catalyzes the
transfer of a terminal galactose to N-acetyllactosamine to create Galα (1, 3) Gal. This …

The catalytic domain of bovine α1→ 3-galactosyltransferase (α3GalT), residues 80–368,
have been cloned and expressed, in Escherichia coli. Using a sequential purification …