[HTML][HTML] Advances of medical nanorobots for future cancer treatments

X Kong, P Gao, J Wang, Y Fang, KC Hwang - Journal of Hematology & …, 2023 - Springer
Early detection and diagnosis of many cancers is very challenging. Late stage detection of a
cancer always leads to high mortality rates. It is imperative to develop novel and more …

Overview of nanoparticulate strategies for solubility enhancement of poorly soluble drugs

KU Khan, MU Minhas, SF Badshah, M Suhail, A Ahmad… - Life Sciences, 2022 - Elsevier
Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …

Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers

Z Zhao, A Ukidve, V Krishnan, S Mitragotri - Advanced drug delivery …, 2019 - Elsevier
Over the years, a plethora of materials–natural and synthetic–have been engineered at a
nanoscopic level and explored for drug delivery. Nanocarriers based on such materials …

Graphene-based nanomaterials and their potentials in advanced drug delivery and cancer therapy

J Liu, J Dong, T Zhang, Q Peng - Journal of Controlled Release, 2018 - Elsevier
The continuing increase of cancer morbidity and death rate requires efficient therapeutic
strategies. The traditional chemotherapy usually fails to treat cancer or prolong survival rate …

Challenging the fundamental conjectures in nanoparticle drug delivery for chemotherapy treatment of solid cancers

J Yang, X Wang, B Wang, K Park, K Wooley… - Advanced Drug Delivery …, 2022 - Elsevier
Nanomedicines for cancer treatment have been studied extensively over the last few
decades. Yet, only five anticancer nanomedicines have received approvals from the United …

Evolution of nanomedicine formulations for targeted delivery and controlled release

S Puri, M Mazza, G Roy, RM England, L Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Nanotechnology research over the past several decades has been aimed primarily at
improving the physicochemical properties of small molecules to produce druggable …

A review on albumin as a biomaterial for ocular drug delivery

R Tiwari, NK Sethiya, AS Gulbake, NK Mehra… - International Journal of …, 2021 - Elsevier
Abstract Development of ocular drug delivery system is one of the most technically
challenging tasks, when compared with other routes of drug delivery. Eye (an intricate …

Can machine learning predict drug nanocrystals?

Y He, Z Ye, X Liu, Z Wei, F Qiu, HF Li, Y Zheng… - Journal of Controlled …, 2020 - Elsevier
Nanocrystals have exhibited great advantage for enhancing the dissolution rate of water
insoluble drugs due to the reduced size to nanoscale. However, current pharmaceutical …

[HTML][HTML] Microneedles in action: microneedling and microneedles-assisted transdermal delivery

DJ Lim, HJ Kim - Polymers, 2022 - mdpi.com
Human skin is a multilayered physiochemical barrier protecting the human body. The
stratum corneum (SC) is the outermost keratinized layer of skin through which only …

Microfluidic fabrication and characterization of Sorafenib-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery

N Tahir, A Madni, W Li, A Correia, MM Khan… - International Journal of …, 2020 - Elsevier
Lipid polymer hybrid nanoparticles (LPHNPs) have been merged as potential nanocarriers
for treatment of cancer. In the present study, LPHNPs loaded with Sorafenib (SFN) were …