Mosaic loss of chromosome Y and cardiovascular disease
S Sano, K Walsh - Nature Reviews Cardiology, 2024 - nature.com
Mosaic loss of chromosome Y (mLOY) refers to the condition in male individuals in which a
detectable fraction of cells lose the Y chromosome. Prevalent in haematopoietic cells, this …
detectable fraction of cells lose the Y chromosome. Prevalent in haematopoietic cells, this …
Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure
K Horitani, NW Chavkin, Y Arai, Y Wang… - Nature Cardiovascular …, 2024 - nature.com
Heart failure affects millions of people worldwide, with men exhibiting a higher incidence
than women. Our previous work has shown that mosaic loss of the Y chromosome (LOY) in …
than women. Our previous work has shown that mosaic loss of the Y chromosome (LOY) in …
Physiology in Perspective
C England - Physiology, 2024 - journals.physiology.org
This issue of Physiology contains four exciting reviews that cover the breadth of physiology
and pathophysiology. First, we explore how microglia play a crucial role in energy …
and pathophysiology. First, we explore how microglia play a crucial role in energy …