The two axes of the renin–angiotensin system include the classical ACE/Ang II/AT1 axis and
the counter-regulatory ACE2/Ang-(1-7)/Mas1 axis. ACE2 is a multifunctional …

Chronic and acute respiratory diseases pose a major problem for public health worldwide
due to the high morbidity and mortality rates, while treatment options remain mostly …

Combining optimized spike (S) protein-encoding mRNA vaccines to target multiple SARS-
CoV-2 variants could improve control of the COVID-19 pandemic. We compare monovalent …

Since the first description of COVID-19 infection, among clinical manifestations of the
disease, including fever, dyspnea, cough, and fatigue, it was observed a high incidence of …

Microglia, brain-resident innate immune cells, have been extensively studied in
neurodegenerative contexts like Alzheimer's disease. The Coronavirus disease 2019 …

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), resulted in an ongoing pandemic with millions of deaths …

Objectives First, to describe SARS-CoV-2 T cell and antibody responses in a prospective
cohort of healthcare workers that suffered from mild to moderate COVID-19 approximately …

SARS-CoV-2 is responsible for the COVID-19 pandemic. The structure of SARS-CoV-2 and
most of its proteins of have been deciphered. SARS-CoV-2 enters cells through the …

Abstract The coronavirus disease 2019 (COVID-19) represents a global health and
economic challenge. Hepatic injuries have been approved to be associated with severe …

Abstract Coronavirus disease 2019 (COVID-19) is a real challenge for humanity with high
morbidity and mortality. Despite being primarily a respiratory illness, COVID-19 can affect …