Nosologically, Alzheimer disease (AD) is no one single disorder. Evidence is provided that a
small proportion of 5% to 10% of all Alzheimer cases is caused by missense mutations in …

Reactive oxygen species (ROS), as superoxide and its metabolites, have important roles in
vascular homeostasis as they are involved in various signaling processes. In many …

We previously showed that resveratrol (3, 4′, 5-trihydroxystilbene) stimulates NO
production and is cardioprotective in rat heart subjected to ischemia–reperfusion (I/R rat …

Sleep apnea syndrome has been shown to be associated with decreased levels of
circulating nitric oxide (NO) after waking up from sleep. In this study we investigated …

We examined whether cGMP-dependent protein kinase (PKG) and mitochondrial ATP-
sensitive potassium (KATP) channels are involved in S-nitroso-N-acetyl penicillamine …

Oridonin is a diterpenoid isolated from Rabdosia rubescens (Hemsl.) Hara, a well-known
herbal tea in China with many health benefits. To provide a better understanding of the …

Myocardial function is dependent on a constant supply of oxygen from the coronary
circulation. A reduction of oxygen supply due to coronary obstruction results in myocardial …

Nitric oxide is a key player among the numerous mediators of endothelial homeostasis and
cardiac contractility and is thereby involved in the pathogenic processes leading to vascular …

In the present report we investigated the differential expression of three types of nitric oxide
synthase (NOS) in the left ventricle after myocardial infarction in rats. One, 3, 7, 14, 28 and …

The aging brain is characterized by selective neurochemical changes involving several
neural populations. A deficit in the cholinergic system of the basal forebrain is thought to …